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v1.0.0
ICD-10 Guide
ICD-10 CodesG04.0

G04.0

Billable

Acute disseminated encephalitis and encephalomyelitis (ADEM)

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 G04.0 is a billable code used to indicate a diagnosis of acute disseminated encephalitis and encephalomyelitis (adem).

Key Diagnostic Point:

Acute disseminated encephalitis and encephalomyelitis (ADEM) is a rare neurological disorder characterized by widespread inflammation of the brain and spinal cord. It typically follows a viral infection, such as measles, mumps, or influenza, or can occur post-vaccination. ADEM is most commonly seen in children but can affect individuals of any age. Clinically, it presents with symptoms such as fever, headache, confusion, seizures, and focal neurological deficits. The condition is thought to be an autoimmune response triggered by the preceding infection, leading to demyelination and neuronal damage. Diagnosis is primarily based on clinical presentation, MRI findings showing lesions in the brain and spinal cord, and the exclusion of other causes of encephalitis. Treatment often involves corticosteroids to reduce inflammation and supportive care. Early recognition and management are crucial to improve outcomes and minimize long-term neurological deficits.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Differentiating ADEM from other forms of encephalitis
  • Need for comprehensive clinical documentation
  • Potential overlap with other neurological conditions
  • Variability in presentation and severity

Audit Risk Factors

  • Inadequate documentation of clinical symptoms
  • Failure to provide imaging results
  • Misclassification of ADEM as viral encephalitis
  • Lack of follow-up documentation

Specialty Focus

Medical Specialties

Neurology

Documentation Requirements

Detailed neurological examination findings, imaging results, and treatment plans.

Common Clinical Scenarios

Patients presenting with acute neurological symptoms following a viral illness.

Billing Considerations

Ensure clear documentation of symptom onset and progression to support the diagnosis.

Pediatrics

Documentation Requirements

History of recent infections, vaccination status, and developmental milestones.

Common Clinical Scenarios

Children with sudden onset of neurological deficits after a viral infection.

Billing Considerations

Consider age-related factors in symptom presentation and response to treatment.

Coding Guidelines

Inclusion Criteria

Use G04.0 When
  • Follow the official ICD
  • CM coding guidelines for neurological disorders
  • ADEM should be coded based on clinical documentation and confirmed diagnosis through imaging and laboratory tests

Exclusion Criteria

Do NOT use G04.0 When
No specific exclusions found.

Related ICD-10 Codes

Related CPT Codes

70450CPT Code

CT scan of the head

Clinical Scenario

Used to evaluate for acute changes in brain structure.

Documentation Requirements

Document indication for imaging and findings.

Specialty Considerations

Neurologists should ensure imaging correlates with clinical findings.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of ADEM, improving the accuracy of data collection and reimbursement processes.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of ADEM, improving the accuracy of data collection and reimbursement processes.

Reimbursement & Billing Impact

reimbursement processes.

Resources

Clinical References

  • •
    CDC - Encephalitis

Coding & Billing References

  • •
    CDC - Encephalitis

Frequently Asked Questions

What are the common symptoms of ADEM?

Common symptoms include fever, headache, confusion, seizures, and focal neurological deficits, often following a viral infection.