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ICD-10 Guide
ICD-10 CodesI42.3

I42.3

Billable

Endomyocardial (eosinophilic) disease

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/06/2025

Code Description

ICD-10 I42.3 is a billable code used to indicate a diagnosis of endomyocardial (eosinophilic) disease.

Key Diagnostic Point:

Endomyocardial (eosinophilic) disease is characterized by eosinophilic infiltration of the myocardium, leading to inflammation and potential fibrosis. Clinically, patients may present with symptoms of heart failure, arrhythmias, or chest pain, often accompanied by a history of allergic conditions or drug reactions that could trigger eosinophilia. The anatomy involved primarily includes the myocardium, with possible involvement of the endocardium. Disease progression can lead to significant myocardial damage, resulting in dilated cardiomyopathy and impaired cardiac function. Diagnostic considerations include echocardiography, MRI, and endomyocardial biopsy, which can confirm eosinophilic infiltration. Blood tests to assess eosinophil counts and potential underlying causes of eosinophilia are also critical in the diagnostic process.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Diagnostic complexity: Requires specialized tests and clinical correlation.
  • Treatment complexity: May involve corticosteroids or immunosuppressive therapy.
  • Documentation requirements: Detailed clinical history and diagnostic findings are essential.
  • Coding specificity: Requires accurate identification of eosinophilic involvement.

Audit Risk Factors

  • Common coding errors: Misclassification with other cardiomyopathies.
  • Documentation gaps: Incomplete clinical history or lack of biopsy results.
  • Billing challenges: Potential denials due to insufficient evidence of eosinophilic disease.

Specialty Focus

Medical Specialties

Cardiology

Documentation Requirements

Standard ICD-10-CM documentation requirements apply

Common Clinical Scenarios

Various clinical presentations within this specialty area

Billing Considerations

Follow specialty-specific billing guidelines

Allergy and Immunology

Documentation Requirements

Standard ICD-10-CM documentation requirements apply

Common Clinical Scenarios

Various clinical presentations within this specialty area

Billing Considerations

Follow specialty-specific billing guidelines

Related ICD-10 Codes

Related CPT Codes

CPT Code

Clinical Scenario

Documentation Requirements

CPT Code

Clinical Scenario

Documentation Requirements

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

Endomyocardial (eosinophilic) disease has significant clinical implications, particularly in populations with underlying allergic conditions. Its impact on population health is notable due to the potential for severe heart failure and arrhythmias, which can lead to increased healthcare utilization. Quality measures should focus on early diagnosis and appropriate management to improve outcomes. Epidemiologically, eosinophilic myocarditis may be underdiagnosed, highlighting the need for increased awareness among healthcare providers.

ICD-9 vs ICD-10

Endomyocardial (eosinophilic) disease has significant clinical implications, particularly in populations with underlying allergic conditions. Its impact on population health is notable due to the potential for severe heart failure and arrhythmias, which can lead to increased healthcare utilization. Quality measures should focus on early diagnosis and appropriate management to improve outcomes. Epidemiologically, eosinophilic myocarditis may be underdiagnosed, highlighting the need for increased awareness among healthcare providers.

Reimbursement & Billing Impact

Reimbursement may be affected by the completeness of documentation, particularly if the diagnosis is not clearly established. Common denials can occur if there is insufficient evidence of eosinophilic infiltration or if the condition is misclassified. Best practices include ensuring that all diagnostic tests are documented and that the clinical rationale for the diagnosis is clearly articulated in the medical record.

Resources

Clinical References

  • •
    ICD-10 Official Guidelines for I00-I99
  • •
    Clinical Documentation Requirements

Coding & Billing References

  • •
    ICD-10 Official Guidelines for I00-I99
  • •
    Clinical Documentation Requirements

Frequently Asked Questions

What specific conditions are covered by I42.3?

I42.3 specifically covers endomyocardial disease characterized by eosinophilic infiltration, which may arise from various etiologies including allergic reactions, drug-induced eosinophilia, or certain infections. It is crucial to differentiate this from other types of cardiomyopathy.

When should I42.3 be used instead of related codes?

I42.3 should be used when there is clear evidence of eosinophilic infiltration of the myocardium, confirmed through biopsy or imaging, and when symptoms align with eosinophilic myocarditis. It is important to differentiate it from other cardiomyopathies that do not involve eosinophilic processes.

What documentation supports I42.3?

Documentation should include a detailed clinical history, laboratory results showing elevated eosinophil counts, imaging studies, and histopathological findings from endomyocardial biopsy confirming eosinophilic infiltration.