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ICD-10 Guide
ICD-10 CodesJ84.841

J84.841

Neuroendocrine cell hyperplasia of infancy

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/06/2025

Code Description

ICD-10 J84.841 is a billable code used to indicate a diagnosis of neuroendocrine cell hyperplasia of infancy.

Key Diagnostic Point:

Neuroendocrine cell hyperplasia of infancy (NEHI) is a rare lung condition characterized by an abnormal proliferation of neuroendocrine cells in the lungs of infants. Clinically, it presents with respiratory distress, recurrent wheezing, and chronic cough, often leading to significant breathing difficulties. The condition primarily affects the small airways, resulting in obstructive lung disease. The pathophysiology involves hyperplasia of neuroendocrine cells, which may disrupt normal lung function and contribute to airway hyperreactivity. Diagnosis typically involves a combination of clinical evaluation, imaging studies such as chest X-rays or CT scans, and sometimes lung biopsy to confirm the presence of neuroendocrine cell hyperplasia. Disease progression can vary, with some infants experiencing spontaneous resolution, while others may develop chronic respiratory issues. Early identification and management are crucial to improving outcomes, as the condition can lead to long-term respiratory complications if left untreated.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Diagnostic complexity: Requires specialized imaging and possibly biopsy for confirmation.
  • Treatment complexity: Management may involve a multidisciplinary approach including pulmonology and pediatrics.
  • Documentation requirements: Detailed clinical documentation is necessary to support diagnosis and treatment.
  • Coding specificity: Requires precise coding to differentiate from other respiratory conditions.

Audit Risk Factors

  • Common coding errors: Misclassification with other lung diseases.
  • Documentation gaps: Insufficient clinical details to support diagnosis.
  • Billing challenges: Potential denials if documentation does not clearly establish the diagnosis.

Specialty Focus

Medical Specialties

Pediatrics

Documentation Requirements

Standard ICD-10-CM documentation requirements apply

Common Clinical Scenarios

Various clinical presentations within this specialty area

Billing Considerations

Follow specialty-specific billing guidelines

Pulmonology

Documentation Requirements

Standard ICD-10-CM documentation requirements apply

Common Clinical Scenarios

Various clinical presentations within this specialty area

Billing Considerations

Follow specialty-specific billing guidelines

Related CPT Codes

CPT Code

Clinical Scenario

Documentation Requirements

CPT Code

Clinical Scenario

Documentation Requirements

CPT Code

Clinical Scenario

Documentation Requirements

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

Neuroendocrine cell hyperplasia of infancy has significant clinical implications, as it can lead to chronic respiratory issues if not identified and managed early. The condition affects a small but vulnerable population of infants, highlighting the need for awareness among healthcare providers. Understanding NEHI can improve quality measures related to pediatric respiratory health and inform healthcare utilization patterns, as timely intervention can reduce hospitalizations and long-term complications.

ICD-9 vs ICD-10

Neuroendocrine cell hyperplasia of infancy has significant clinical implications, as it can lead to chronic respiratory issues if not identified and managed early. The condition affects a small but vulnerable population of infants, highlighting the need for awareness among healthcare providers. Understanding NEHI can improve quality measures related to pediatric respiratory health and inform healthcare utilization patterns, as timely intervention can reduce hospitalizations and long-term complications.

Reimbursement & Billing Impact

Reimbursement considerations include ensuring that the diagnosis is well-supported by clinical evidence, as payers may scrutinize claims for rare conditions. Common denials may arise from insufficient documentation or misclassification of the condition. It is essential to follow coding best practices, including using the most specific code available and providing comprehensive clinical notes to justify the diagnosis and treatment provided.

Resources

Clinical References

  • •
    ICD-10 Official Guidelines for J00-J99
  • •
    Clinical Documentation Requirements

Coding & Billing References

  • •
    ICD-10 Official Guidelines for J00-J99
  • •
    Clinical Documentation Requirements

Frequently Asked Questions

What specific conditions are covered by J84.841?

J84.841 specifically covers neuroendocrine cell hyperplasia of infancy, which is characterized by the proliferation of neuroendocrine cells in the lungs, leading to respiratory symptoms in infants.

When should J84.841 be used instead of related codes?

J84.841 should be used when there is a confirmed diagnosis of neuroendocrine cell hyperplasia of infancy, particularly when distinguishing from other interstitial lung diseases or respiratory conditions in infants.

What documentation supports J84.841?

Documentation should include clinical findings, imaging results, and any biopsy reports that confirm neuroendocrine cell hyperplasia. Detailed notes on the patient's respiratory symptoms and treatment response are also essential.