Food protein-induced enterocolitis syndrome
ICD-10 K52.21 is a billable code used to indicate a diagnosis of food protein-induced enterocolitis syndrome.
Food protein-induced enterocolitis syndrome (FPIES) is a non-IgE-mediated gastrointestinal allergy primarily affecting infants and young children. Clinically, it presents with severe vomiting, diarrhea, and dehydration, typically occurring within hours after ingestion of specific food proteins, such as cow's milk or soy. The anatomy involved includes the small intestine and colon, where inflammation and damage occur due to the immune response to the offending proteins. Disease progression can lead to chronic gastrointestinal symptoms, malnutrition, and failure to thrive if not identified and managed appropriately. Diagnostic considerations include a thorough clinical history, elimination diets, and oral food challenges under medical supervision to confirm the specific food triggers. Laboratory tests may show signs of inflammation, but specific IgE tests are usually negative, distinguishing FPIES from other allergic conditions. Early recognition and management are crucial to prevent severe complications and ensure proper growth and development in affected children.
Standard ICD-10-CM documentation requirements apply
Various clinical presentations within this specialty area
Follow specialty-specific billing guidelines
Standard ICD-10-CM documentation requirements apply
Various clinical presentations within this specialty area
Follow specialty-specific billing guidelines
K52.21 specifically covers food protein-induced enterocolitis syndrome, characterized by gastrointestinal symptoms triggered by specific food proteins, primarily in infants and young children.
K52.21 should be used when the clinical presentation aligns with FPIES, particularly when symptoms arise after ingestion of specific food proteins, and other causes of enterocolitis have been ruled out.
Documentation should include a detailed clinical history of symptoms following food intake, results from elimination diets, and any oral food challenge outcomes, along with a record of the patient's growth and nutritional status.
