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ICD-10 Guide
ICD-10 CodesL27.0

L27.0

Billable

Generalized skin eruption due to drugs and medicaments taken internally

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/06/2025

Code Description

ICD-10 L27.0 is a billable code used to indicate a diagnosis of generalized skin eruption due to drugs and medicaments taken internally.

Key Diagnostic Point:

Generalized skin eruption due to drugs and medicaments taken internally, classified under ICD-10 code L27.0, refers to a widespread rash or skin reaction resulting from systemic exposure to pharmacological agents. Clinically, patients may present with various types of eruptions, including maculopapular rashes, urticaria, or even more severe reactions like Stevens-Johnson syndrome. The skin, being the largest organ, can exhibit diverse responses to drugs, often involving the epidermis and dermis layers. Disease progression can vary; some patients may experience immediate reactions, while others may have delayed hypersensitivity responses. Diagnostic considerations include a thorough patient history to identify potential offending agents, physical examination of the skin lesions, and, if necessary, skin tests or biopsies to rule out other dermatological conditions. It is crucial to differentiate drug eruptions from other skin disorders, as management involves discontinuation of the offending medication and symptomatic treatment.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Diagnostic complexity: Requires careful assessment of patient history and potential drug interactions.
  • Treatment complexity: Management may involve multiple specialists, especially in severe cases.
  • Documentation requirements: Detailed documentation of drug history and clinical findings is essential.
  • Coding specificity: Requires accurate identification of the drug causing the eruption.

Audit Risk Factors

  • Common coding errors: Misidentification of the drug causing the eruption.
  • Documentation gaps: Incomplete drug history or lack of clinical details.
  • Billing challenges: Potential denials if the relationship between the drug and eruption is not clearly established.

Specialty Focus

Medical Specialties

Dermatology

Documentation Requirements

Standard ICD-10-CM documentation requirements apply

Common Clinical Scenarios

Various clinical presentations within this specialty area

Billing Considerations

Follow specialty-specific billing guidelines

Allergy and Immunology

Documentation Requirements

Standard ICD-10-CM documentation requirements apply

Common Clinical Scenarios

Various clinical presentations within this specialty area

Billing Considerations

Follow specialty-specific billing guidelines

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ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The clinical significance of L27.0 lies in its potential to indicate serious adverse drug reactions, which can impact patient safety and treatment outcomes. Understanding the epidemiology of drug eruptions is crucial for population health, as these reactions can lead to increased healthcare utilization, including emergency visits and hospitalizations. Quality measures may include monitoring for adverse drug reactions and ensuring timely identification and management of drug-induced skin conditions.

ICD-9 vs ICD-10

The clinical significance of L27.0 lies in its potential to indicate serious adverse drug reactions, which can impact patient safety and treatment outcomes. Understanding the epidemiology of drug eruptions is crucial for population health, as these reactions can lead to increased healthcare utilization, including emergency visits and hospitalizations. Quality measures may include monitoring for adverse drug reactions and ensuring timely identification and management of drug-induced skin conditions.

Reimbursement & Billing Impact

Reimbursement considerations may vary based on the severity of the eruption and the complexity of the treatment provided. Common denials can occur if there is insufficient documentation linking the drug to the skin condition. Best practices include maintaining clear and detailed records of patient interactions and treatment plans to support claims.

Resources

Clinical References

  • •
    ICD-10 Official Guidelines for L00-L99
  • •
    Clinical Documentation Requirements

Coding & Billing References

  • •
    ICD-10 Official Guidelines for L00-L99
  • •
    Clinical Documentation Requirements

Frequently Asked Questions

What specific conditions are covered by L27.0?

L27.0 encompasses generalized skin eruptions such as drug-induced urticaria, maculopapular rashes, and more severe reactions like drug-induced hypersensitivity syndrome. It is essential to establish a clear link between the eruption and the medication taken.

When should L27.0 be used instead of related codes?

L27.0 should be used when the skin eruption is widespread and directly linked to systemic medication use. If the eruption is localized or due to a specific allergen, other codes like L27.1 may be more appropriate.

What documentation supports L27.0?

Documentation should include a comprehensive drug history, details of the onset and progression of the skin eruption, physical examination findings, and any diagnostic tests performed to rule out other conditions.