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ICD-10 Guide
ICD-10 CodesM05.59

M05.59

Billable

Rheumatoid polyneuropathy with rheumatoid arthritis of multiple sites

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/12/2025

Code Description

ICD-10 M05.59 is a billable code used to indicate a diagnosis of rheumatoid polyneuropathy with rheumatoid arthritis of multiple sites.

Key Diagnostic Point:

Rheumatoid polyneuropathy is a complication of rheumatoid arthritis (RA) characterized by peripheral nerve involvement due to systemic inflammation. RA is an autoimmune disorder that primarily affects synovial joints, leading to chronic inflammation, pain, and eventual joint destruction. In polyneuropathy, multiple peripheral nerves are affected, resulting in symptoms such as numbness, tingling, and weakness, particularly in the extremities. Anatomically, the condition involves the peripheral nervous system, which includes nerves outside the brain and spinal cord. The pathophysiology involves immune-mediated damage to the nerve fibers, often exacerbated by the inflammatory cytokines released during RA flares. Clinically, patients may present with joint pain and swelling in multiple sites, alongside neurological symptoms, complicating the management and treatment of both conditions. Early diagnosis and intervention are crucial to prevent irreversible nerve damage and joint deformities.

Code Complexity Analysis

Complexity Rating: High

High Complexity

Complexity Factors

  • Multiple joint involvement complicates treatment and documentation.
  • Neurological symptoms require additional diagnostic criteria.
  • Differentiation from other neuropathies is necessary.
  • Management may involve interdisciplinary approaches.

Audit Risk Factors

  • Inadequate documentation of neurological symptoms.
  • Failure to specify joint involvement and severity.
  • Misclassification of polyneuropathy as a primary condition.
  • Lack of evidence for disease activity markers.

Specialty Focus

Medical Specialties

Orthopedics

Documentation Requirements

Orthopedic documentation should include imaging studies (X-rays, MRIs) to assess joint damage and functional assessments to evaluate mobility.

Common Clinical Scenarios

Patients may require joint injections or surgical interventions for severe joint deformities.

Billing Considerations

Joint-specific considerations include documenting the range of motion and any deformities present.

Rheumatology

Documentation Requirements

Rheumatologic documentation must include laboratory tests for inflammatory markers (e.g., ESR, CRP) and assessments of disease activity (e.g., DAS28).

Common Clinical Scenarios

Management of RA flares and adjustments in DMARD therapy are common scenarios.

Billing Considerations

Systemic involvement, such as vasculitis or extra-articular manifestations, should be documented.

Physical Medicine

Documentation Requirements

Functional assessments should evaluate the patient's ability to perform activities of daily living and mobility limitations.

Common Clinical Scenarios

Rehabilitation may focus on restoring function post-surgery or managing chronic pain.

Billing Considerations

Assistive devices may be necessary, and their use should be documented.

Coding Guidelines

Inclusion Criteria

Use M05.59 When
  • Follow official coding guidelines for laterality (if applicable), severity of the condition, and type of encounter (initial, follow
  • up, etc
  • Ensure that all relevant symptoms and joint involvement are documented

Exclusion Criteria

Do NOT use M05.59 When
No specific exclusions found.

Related ICD-10 Codes

Related CPT Codes

99214CPT Code

Established patient office visit, level 4

Clinical Scenario

Used for follow-up visits to manage RA and assess neurological symptoms.

Documentation Requirements

Document the patient's history, examination findings, and treatment plan.

Specialty Considerations

Rheumatology and neurology considerations for comprehensive care.

20610CPT Code

Arthrocentesis, aspiration and/or injection into a major joint or bursa

Clinical Scenario

Used for joint injections in patients with RA experiencing significant pain.

Documentation Requirements

Document the joint involved, the procedure performed, and the patient's response.

Specialty Considerations

Orthopedic considerations for joint management.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for greater specificity in coding musculoskeletal conditions, enabling better tracking of complications like polyneuropathy associated with rheumatoid arthritis.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for greater specificity in coding musculoskeletal conditions, enabling better tracking of complications like polyneuropathy associated with rheumatoid arthritis.

Reimbursement & Billing Impact

The transition to ICD-10 has allowed for greater specificity in coding musculoskeletal conditions, enabling better tracking of complications like polyneuropathy associated with rheumatoid arthritis.

Resources

Clinical References

  • •
    American College of Rheumatology Guidelines

Coding & Billing References

  • •
    American College of Rheumatology Guidelines

Frequently Asked Questions

What are the common symptoms of rheumatoid polyneuropathy?

Common symptoms include numbness, tingling, weakness in the extremities, and pain, often accompanied by joint swelling and stiffness due to rheumatoid arthritis.