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ICD-10 Guide
ICD-10 CodesM46.25

M46.25

Billable

Osteomyelitis of vertebra, thoracolumbar region

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/17/2025

Code Description

ICD-10 M46.25 is a billable code used to indicate a diagnosis of osteomyelitis of vertebra, thoracolumbar region.

Key Diagnostic Point:

Osteomyelitis of the thoracolumbar vertebrae is an infection of the bone that can occur due to hematogenous spread, direct inoculation, or contiguous spread from adjacent structures. This condition is characterized by inflammation of the vertebral body and can lead to significant morbidity if not diagnosed and treated promptly. Symptoms may include localized pain, fever, and neurological deficits depending on the extent of the infection and any associated spinal cord involvement. Risk factors include diabetes mellitus, immunosuppression, recent spinal surgery, or trauma. Diagnosis typically involves imaging studies such as MRI or CT scans, which can reveal bone edema, abscess formation, or other changes indicative of infection. Laboratory tests may show elevated inflammatory markers. Treatment often requires a combination of antibiotics and, in some cases, surgical intervention to debride infected tissue or stabilize the spine. Chronic osteomyelitis can lead to complications such as spinal deformities or persistent pain, necessitating long-term management strategies.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Differentiating between acute and chronic osteomyelitis
  • Identifying the specific vertebral levels affected
  • Understanding the underlying causes (e.g., hematogenous vs. contiguous spread)
  • Co-existing conditions such as ankylosing spondylitis or spinal stenosis

Audit Risk Factors

  • Inadequate documentation of the infection's origin
  • Failure to specify acute vs. chronic osteomyelitis
  • Lack of imaging or lab results to support diagnosis
  • Misclassification of the vertebral region affected

Specialty Focus

Medical Specialties

Orthopedic Surgery

Documentation Requirements

Detailed surgical notes, imaging results, and post-operative care plans.

Common Clinical Scenarios

Surgical intervention for osteomyelitis, management of spinal deformities.

Billing Considerations

Ensure clear documentation of the surgical approach and any complications.

Infectious Disease

Documentation Requirements

Comprehensive history of infection, lab results, and antibiotic treatment plans.

Common Clinical Scenarios

Management of osteomyelitis in immunocompromised patients.

Billing Considerations

Document underlying conditions that may predispose to infection.

Coding Guidelines

Inclusion Criteria

Use M46.25 When
  • Follow the official ICD
  • CM coding guidelines, ensuring accurate documentation of the site and type of osteomyelitis
  • Include any relevant comorbidities and specify whether the condition is acute or chronic

Exclusion Criteria

Do NOT use M46.25 When
No specific exclusions found.

Related ICD-10 Codes

Related CPT Codes

22554CPT Code

Percutaneous vertebroplasty

Clinical Scenario

Used in cases of vertebral compression fractures due to osteomyelitis.

Documentation Requirements

Document indications for the procedure and imaging findings.

Specialty Considerations

Orthopedic surgeons should ensure clear documentation of the patient's condition and treatment rationale.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of osteomyelitis, improving the accuracy of data collection and reimbursement processes. M46.25 provides a clear distinction for osteomyelitis in the thoracolumbar region, which aids in clinical management and research.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of osteomyelitis, improving the accuracy of data collection and reimbursement processes. M46.25 provides a clear distinction for osteomyelitis in the thoracolumbar region, which aids in clinical management and research.

Reimbursement & Billing Impact

reimbursement processes. M46.25 provides a clear distinction for osteomyelitis in the thoracolumbar region, which aids in clinical management and research.

Resources

Clinical References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Coding & Billing References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Frequently Asked Questions

What are the common causes of osteomyelitis in the thoracolumbar region?

Common causes include hematogenous spread from distant infections, direct inoculation from trauma or surgery, and contiguous spread from adjacent infections.