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ICD-10 Guide
ICD-10 CodesM46.5

M46.5

Billable

Other infective spondylopathies

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/17/2025

Code Description

ICD-10 M46.5 is a billable code used to indicate a diagnosis of other infective spondylopathies.

Key Diagnostic Point:

Infective spondylopathies refer to inflammatory conditions of the spine caused by infectious agents, which can lead to significant morbidity if not diagnosed and treated promptly. M46.5 encompasses various forms of spondylitis that are not classified under more specific categories, such as ankylosing spondylitis or other known infections. These conditions may arise from bacterial, viral, or fungal infections and can present with symptoms such as localized pain, fever, and neurological deficits due to spinal cord involvement. Diagnosis typically involves imaging studies, such as MRI or CT scans, and laboratory tests to identify the causative organism. Treatment often includes antibiotics or antifungal medications, along with supportive care. The complexity of coding for infective spondylopathies lies in the need for precise documentation of the infectious agent, the extent of spinal involvement, and any associated complications, which can vary significantly among patients.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Variability in clinical presentation and underlying causes
  • Need for precise documentation of infectious agents
  • Differentiation from non-infective spondylopathies
  • Potential for co-existing conditions affecting coding

Audit Risk Factors

  • Inadequate documentation of the infectious agent
  • Failure to specify the extent of spinal involvement
  • Misclassification as non-infective spondylopathy
  • Lack of supporting imaging or lab results

Specialty Focus

Medical Specialties

Rheumatology

Documentation Requirements

Detailed history of symptoms, laboratory results, and imaging studies.

Common Clinical Scenarios

Patients presenting with back pain, fever, and elevated inflammatory markers.

Billing Considerations

Ensure clear documentation of infectious etiology and response to treatment.

Infectious Disease

Documentation Requirements

Identification of the pathogen, treatment regimen, and follow-up results.

Common Clinical Scenarios

Patients with known infections presenting with spinal symptoms.

Billing Considerations

Document the relationship between the infection and spinal symptoms clearly.

Coding Guidelines

Inclusion Criteria

Use M46.5 When
  • According to ICD
  • 10 guidelines, M46
  • 5 should be used when the infective nature of the spondylopathy is confirmed
  • Coders must ensure that the documentation supports the diagnosis, including the specific infectious agent and any complications

Exclusion Criteria

Do NOT use M46.5 When
  • Exclusion criteria include conditions that are not infectious in nature

Related ICD-10 Codes

Related CPT Codes

72148CPT Code

MRI of the spine

Clinical Scenario

Used to evaluate suspected infective spondylopathy.

Documentation Requirements

Indication for MRI must be clearly documented.

Specialty Considerations

Rheumatology and Infectious Disease specialists should ensure imaging correlates with clinical findings.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of infective spondylopathies, improving the accuracy of data collection and reimbursement processes. M46.5 provides a distinct code for conditions that were previously lumped together, allowing for better tracking of infectious spine diseases.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of infective spondylopathies, improving the accuracy of data collection and reimbursement processes. M46.5 provides a distinct code for conditions that were previously lumped together, allowing for better tracking of infectious spine diseases.

Reimbursement & Billing Impact

reimbursement processes. M46.5 provides a distinct code for conditions that were previously lumped together, allowing for better tracking of infectious spine diseases.

Resources

Clinical References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Coding & Billing References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Frequently Asked Questions

What are the common causes of infective spondylopathies?

Common causes include bacterial infections such as staphylococcus, tuberculosis, and fungal infections, particularly in immunocompromised patients.

How can I differentiate between infective and non-infective spondylopathies?

Differentiation is based on clinical presentation, laboratory findings, and imaging studies that reveal infectious processes such as abscesses or significant inflammation.