ICD-10 Logo
ICDxICD-10 Medical Coding
ICD-10 Logo
ICDxICD-10 Medical Coding
ICD 10 CodesDiagnoses
ICD 10 CodesDiagnoses
ICD-10 Logo
ICDxICD-10 Medical Coding

Comprehensive ICD-10-CM code reference with AI-powered search capabilities.

© 2025 ICD Code Compass. All rights reserved.

Browse

  • All Chapters
  • All Categories
  • Diagnoses

Tools

  • AI Code Search
ICD-10-CM codes are maintained by the CDC and CMS. This tool is for reference purposes only.
v1.0.0
ICD-10 Guide
ICD-10 CodesM46.50

M46.50

Billable

Other infective spondylopathies, site unspecified

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/17/2025

Code Description

ICD-10 M46.50 is a billable code used to indicate a diagnosis of other infective spondylopathies, site unspecified.

Key Diagnostic Point:

Infective spondylopathies refer to inflammatory conditions of the spine caused by infectious agents, which can include bacteria, viruses, fungi, or parasites. M46.50 specifically denotes cases where the site of infection within the spine is unspecified. These conditions can lead to significant morbidity due to pain, neurological deficits, and potential complications such as abscess formation or sepsis. Common infectious agents include Staphylococcus aureus, Mycobacterium tuberculosis, and various fungi. Symptoms may include localized back pain, fever, and neurological symptoms if the spinal cord is involved. Diagnosis typically involves imaging studies such as MRI or CT scans, along with laboratory tests to identify the causative organism. Treatment often requires a combination of antibiotics or antifungal medications and, in some cases, surgical intervention to decompress the spinal cord or remove infected tissue. The complexity of coding for infective spondylopathies arises from the need for precise documentation of the infectious agent, the extent of the disease, and any associated complications.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Variability in clinical presentation and symptoms
  • Need for precise documentation of infectious agents
  • Differentiation from non-infective spondylopathies
  • Potential for multiple sites of infection

Audit Risk Factors

  • Insufficient documentation of the infectious agent
  • Lack of imaging or lab results to support diagnosis
  • Inconsistent use of terminology in clinical notes
  • Failure to specify the extent of the disease

Specialty Focus

Medical Specialties

Infectious Disease

Documentation Requirements

Detailed notes on the infectious agent, treatment plan, and response to therapy.

Common Clinical Scenarios

Patients presenting with back pain and fever, suspected osteomyelitis, or abscess formation.

Billing Considerations

Ensure that all lab results and imaging studies are included in the documentation to support the diagnosis.

Orthopedic Surgery

Documentation Requirements

Surgical notes detailing the procedure, findings, and any specimens sent for culture.

Common Clinical Scenarios

Surgical intervention for abscess drainage or decompression of the spinal cord.

Billing Considerations

Document the rationale for surgery and any pre-operative imaging findings.

Coding Guidelines

Inclusion Criteria

Use M46.50 When
  • According to ICD
  • 10 coding guidelines, M46
  • 50 should be used when the documentation specifies an infective spondylopathy without a defined site
  • Coders must ensure that the clinical documentation supports the diagnosis and that no more specific code is applicable

Exclusion Criteria

Do NOT use M46.50 When
No specific exclusions found.

Related ICD-10 Codes

Related CPT Codes

63030CPT Code

Laminectomy, facetectomy, and foraminotomy

Clinical Scenario

Used when surgical intervention is required for decompression due to infection.

Documentation Requirements

Surgical notes must detail the procedure and findings.

Specialty Considerations

Orthopedic surgeons should ensure that the diagnosis is clearly linked to the surgical procedure.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of conditions like infective spondylopathies, improving the ability to track and manage these conditions. However, the increased specificity also requires more detailed documentation from providers.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of conditions like infective spondylopathies, improving the ability to track and manage these conditions. However, the increased specificity also requires more detailed documentation from providers.

Reimbursement & Billing Impact

The transition to ICD-10 has allowed for more specific coding of conditions like infective spondylopathies, improving the ability to track and manage these conditions. However, the increased specificity also requires more detailed documentation from providers.

Resources

Clinical References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Coding & Billing References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Frequently Asked Questions

What is the difference between M46.50 and M46.40?

M46.50 is used when the site of infection is unspecified, while M46.40 specifies infective spondylopathy in the lumbar region. Accurate documentation is crucial to determine the appropriate code.