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ICD-10 Guide
ICD-10 CodesN05.4

N05.4

Billable

Unspecified nephritic syndrome with diffuse endocapillary proliferative glomerulonephritis

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/18/2025

Code Description

ICD-10 N05.4 is a billable code used to indicate a diagnosis of unspecified nephritic syndrome with diffuse endocapillary proliferative glomerulonephritis.

Key Diagnostic Point:

Unspecified nephritic syndrome with diffuse endocapillary proliferative glomerulonephritis is characterized by the presence of nephritic syndrome symptoms, including hematuria, proteinuria, and hypertension, alongside diffuse endocapillary proliferation of glomerular cells. This condition often results from various underlying etiologies, including infections, autoimmune diseases, or idiopathic causes. Clinically, patients may present with edema, oliguria, and elevated serum creatinine levels. Renal biopsy findings typically reveal glomerular hypercellularity, often with an increase in mesangial and endothelial cells, and may show immune complex deposition. Management involves addressing the underlying cause, controlling blood pressure, and may include corticosteroids or immunosuppressive therapy depending on the severity and etiology. Regular monitoring of renal function and proteinuria is essential to assess treatment response and progression of the disease.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Variety of underlying causes leading to nephritic syndrome
  • Need for precise documentation of clinical findings
  • Differentiation from nephrotic syndrome
  • Potential for overlapping symptoms with other renal conditions

Audit Risk Factors

  • Inadequate documentation of clinical findings
  • Failure to specify the underlying cause of nephritic syndrome
  • Misclassification with nephrotic syndrome
  • Lack of follow-up documentation on treatment response

Specialty Focus

Medical Specialties

Nephrology

Documentation Requirements

Detailed clinical history, laboratory results, and imaging studies.

Common Clinical Scenarios

Patients presenting with acute kidney injury, chronic kidney disease, or unexplained proteinuria.

Billing Considerations

Ensure accurate documentation of renal biopsy findings and treatment plans.

Internal Medicine

Documentation Requirements

Comprehensive patient history, physical examination findings, and management plans.

Common Clinical Scenarios

Management of patients with systemic diseases affecting the kidneys.

Billing Considerations

Document any comorbid conditions that may influence renal function.

Coding Guidelines

Inclusion Criteria

Use N05.4 When
  • Follow the official ICD
  • CM coding guidelines, ensuring that the code is used when the specific cause of nephritic syndrome is not documented
  • Include additional codes for any underlying conditions or complications

Exclusion Criteria

Do NOT use N05.4 When
No specific exclusions found.

Related ICD-10 Codes

Related CPT Codes

50360CPT Code

Renal biopsy

Clinical Scenario

Used when nephritic syndrome is suspected and renal histology is needed.

Documentation Requirements

Indication for biopsy, consent, and procedure details.

Specialty Considerations

Nephrology specialists should document the rationale for biopsy.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 allows for more specific coding of nephritic syndromes, improving data accuracy and facilitating better patient management and research.

ICD-9 vs ICD-10

The transition to ICD-10 allows for more specific coding of nephritic syndromes, improving data accuracy and facilitating better patient management and research.

Reimbursement & Billing Impact

The transition to ICD-10 allows for more specific coding of nephritic syndromes, improving data accuracy and facilitating better patient management and research.

Resources

Clinical References

  • •
    American Academy of Nephrology

Coding & Billing References

  • •
    American Academy of Nephrology

Frequently Asked Questions

What are the key symptoms of nephritic syndrome?

Key symptoms include hematuria, proteinuria, hypertension, and edema. Patients may also experience oliguria and renal insufficiency.