Primary membranous nephropathy with isolated proteinuria
ICD-10 N06.21 is a billable code used to indicate a diagnosis of primary membranous nephropathy with isolated proteinuria.
Primary membranous nephropathy (PMN) is a kidney disorder characterized by the presence of immune complex deposits along the glomerular basement membrane, leading to increased permeability and resultant proteinuria. In cases classified under N06.21, patients exhibit isolated proteinuria, meaning that protein is present in the urine without significant hematuria or renal impairment. This condition is often idiopathic but can also be associated with secondary causes such as infections, drugs, or malignancies. The isolated proteinuria can be detected through urinalysis, and patients may present with symptoms such as edema or hypertension. Diagnosis typically involves serological tests, kidney biopsy, and imaging studies to rule out other causes of nephropathy. Genetic factors may also play a role, particularly in hereditary forms of nephropathy, which can complicate the clinical picture. Management focuses on controlling symptoms and addressing any underlying causes, with the potential for immunosuppressive therapy in more severe cases.
Detailed clinical notes on patient history, lab results, and treatment plans.
Patients presenting with edema, hypertension, or abnormal urinalysis findings.
Ensure that all relevant lab tests and imaging studies are documented to support the diagnosis.
Genetic testing results and family history of nephropathy.
Patients with a family history of kidney disease or unexplained nephropathy.
Document the rationale for genetic testing and any findings that may influence treatment.
Used to confirm the presence of proteinuria in patients suspected of nephropathy.
Document the results of the urinalysis and any follow-up tests.
Nephrologists should ensure that urinalysis results are clearly linked to the diagnosis.
Isolated proteinuria indicates that protein is present in the urine without significant hematuria or renal impairment, which is a key diagnostic criterion for primary membranous nephropathy.
