Secondary membranous nephropathy with isolated proteinuria
ICD-10 N06.22 is a billable code used to indicate a diagnosis of secondary membranous nephropathy with isolated proteinuria.
Secondary membranous nephropathy is characterized by the presence of immune complex deposition in the glomerular capillary walls, leading to increased permeability and resultant proteinuria. This condition is often associated with underlying diseases such as infections, malignancies, or autoimmune disorders. Isolated proteinuria refers to the presence of protein in the urine without significant hematuria or other urinary abnormalities. In cases of secondary membranous nephropathy, the proteinuria can be significant, often exceeding 3.5 grams per day, which is indicative of nephrotic syndrome. The diagnosis typically involves a combination of clinical evaluation, laboratory tests, and imaging studies. Genetic testing may be considered in cases where hereditary nephropathy is suspected, particularly if there is a family history of kidney disease. Understanding the underlying cause of the nephropathy is crucial for management and treatment, as addressing the primary condition can lead to resolution of the nephropathy and associated proteinuria.
Detailed clinical history, laboratory results, and imaging studies.
Patients presenting with edema, hypertension, and significant proteinuria.
Ensure documentation reflects the severity of proteinuria and any associated symptoms.
Family history, results of genetic testing, and interpretation of findings.
Patients with a family history of kidney disease or unexplained nephropathy.
Document the rationale for genetic testing and its implications for treatment.
Used to assess lipid levels in patients with nephrotic syndrome.
Document the reason for lipid panel testing in the context of nephropathy.
Nephrologists should ensure lipid levels are monitored due to increased cardiovascular risk.
Isolated proteinuria indicates that the protein loss is significant enough to warrant attention but may not be accompanied by other urinary abnormalities. It is crucial for diagnosis and management.
