ICD-10 Logo
ICDxICD-10 Medical Coding
ICD-10 Logo
ICDxICD-10 Medical Coding
ICD 10 CodesDiagnoses
ICD 10 CodesDiagnoses
ICD-10 Logo
ICDxICD-10 Medical Coding

Comprehensive ICD-10-CM code reference with AI-powered search capabilities.

© 2025 ICD Code Compass. All rights reserved.

Browse

  • All Chapters
  • All Categories
  • Diagnoses

Tools

  • AI Code Search
ICD-10-CM codes are maintained by the CDC and CMS. This tool is for reference purposes only.
v1.0.0
ICD-10 Guide
ICD-10 CodesN06.3

N06.3

Billable

Isolated proteinuria with diffuse mesangial proliferative glomerulonephritis

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/18/2025

Code Description

ICD-10 N06.3 is a billable code used to indicate a diagnosis of isolated proteinuria with diffuse mesangial proliferative glomerulonephritis.

Key Diagnostic Point:

Isolated proteinuria with diffuse mesangial proliferative glomerulonephritis is characterized by the presence of protein in the urine without significant hematuria or other renal dysfunction. This condition is often associated with diffuse mesangial proliferation, which indicates an increase in the number of mesangial cells in the glomeruli, leading to potential alterations in glomerular filtration. The etiology may include hereditary nephropathies, autoimmune diseases, or infections. Patients may present with mild to moderate proteinuria, and the condition can be a marker for underlying systemic diseases. Diagnosis typically involves urinalysis, serum creatinine levels, and possibly renal biopsy to assess the extent of mesangial proliferation. Genetic testing may be indicated in cases with a suspected hereditary component, particularly in younger patients or those with a family history of kidney disease. Management focuses on addressing the underlying cause and monitoring renal function over time.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Differentiation from other types of glomerulonephritis
  • Need for comprehensive documentation of proteinuria levels
  • Potential overlap with hereditary nephropathies
  • Requirement for renal biopsy results for accurate coding

Audit Risk Factors

  • Inadequate documentation of proteinuria levels
  • Failure to document renal biopsy results
  • Misclassification of glomerular disorders
  • Lack of clarity on associated systemic conditions

Specialty Focus

Medical Specialties

Nephrology

Documentation Requirements

Detailed urinalysis results, renal function tests, and biopsy findings.

Common Clinical Scenarios

Patients presenting with unexplained proteinuria, family history of kidney disease.

Billing Considerations

Ensure clear documentation of the absence of hematuria and the specific type of glomerulonephritis.

Genetics

Documentation Requirements

Family history, genetic testing results, and clinical findings related to hereditary nephropathies.

Common Clinical Scenarios

Patients with a suspected genetic predisposition to kidney disease.

Billing Considerations

Document any genetic testing performed and its implications for diagnosis.

Coding Guidelines

Inclusion Criteria

Use N06.3 When
  • Follow the official ICD
  • CM coding guidelines, ensuring accurate documentation of the condition's specifics, including the absence of hematuria and the results of any renal biopsies
  • Include any relevant systemic diseases that may contribute to the diagnosis

Exclusion Criteria

Do NOT use N06.3 When
No specific exclusions found.

Related ICD-10 Codes

Related CPT Codes

81002CPT Code

Urinalysis, automated, with microscopy

Clinical Scenario

Used to confirm the presence of proteinuria in patients suspected of glomerular disorders.

Documentation Requirements

Document the results of the urinalysis, including protein levels.

Specialty Considerations

Nephrologists should ensure that urinalysis results are clearly linked to the diagnosis.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 allows for more specific coding of isolated proteinuria and associated conditions, improving the accuracy of patient records and facilitating better management of glomerular disorders.

ICD-9 vs ICD-10

The transition to ICD-10 allows for more specific coding of isolated proteinuria and associated conditions, improving the accuracy of patient records and facilitating better management of glomerular disorders.

Reimbursement & Billing Impact

The transition to ICD-10 allows for more specific coding of isolated proteinuria and associated conditions, improving the accuracy of patient records and facilitating better management of glomerular disorders.

Resources

Clinical References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Coding & Billing References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Frequently Asked Questions

What is the significance of isolated proteinuria?

Isolated proteinuria can indicate underlying kidney issues, including glomerular disorders, and may require further evaluation to determine the cause and appropriate management.