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ICD-10 Guide
ICD-10 CodesN06.5

N06.5

Billable

Isolated proteinuria with diffuse mesangiocapillary glomerulonephritis

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/18/2025

Code Description

ICD-10 N06.5 is a billable code used to indicate a diagnosis of isolated proteinuria with diffuse mesangiocapillary glomerulonephritis.

Key Diagnostic Point:

Isolated proteinuria with diffuse mesangiocapillary glomerulonephritis is characterized by the presence of protein in the urine without significant hematuria or other renal symptoms. This condition is often associated with diffuse mesangiocapillary glomerulonephritis, a type of kidney disease that affects the glomeruli, leading to inflammation and damage. The mesangial cells proliferate, and there is an increase in the mesangial matrix, which can result in a thickening of the capillary walls. Patients may present with varying degrees of proteinuria, and the condition can be hereditary or secondary to other diseases. Genetic factors play a significant role in the development of this condition, and genetic testing may be warranted to identify specific mutations associated with hereditary nephropathies. Diagnosis typically involves urinalysis, serum creatinine levels, and possibly a kidney biopsy to confirm the presence of mesangiocapillary changes. Management focuses on controlling proteinuria and addressing any underlying causes.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Differentiating between isolated proteinuria and other forms of proteinuria.
  • Understanding the relationship between hereditary nephropathy and glomerular disorders.
  • Identifying the need for genetic testing and its implications.
  • Navigating the documentation requirements for associated conditions.

Audit Risk Factors

  • Inadequate documentation of proteinuria levels.
  • Failure to document the presence of mesangiocapillary changes.
  • Lack of genetic testing results in the medical record.
  • Misclassification of the type of glomerulonephritis.

Specialty Focus

Medical Specialties

Nephrology

Documentation Requirements

Detailed urinalysis results, kidney function tests, and biopsy reports.

Common Clinical Scenarios

Patients presenting with unexplained proteinuria, family history of kidney disease, or abnormal kidney function tests.

Billing Considerations

Ensure that all relevant laboratory and imaging studies are documented to support the diagnosis.

Genetics

Documentation Requirements

Genetic testing results and family history documentation.

Common Clinical Scenarios

Patients with a known family history of nephropathy or unexplained renal disease.

Billing Considerations

Documentation of genetic counseling and testing is crucial for accurate coding.

Coding Guidelines

Inclusion Criteria

Use N06.5 When
  • According to ICD
  • 10 guidelines, N06
  • 5 should be used when isolated proteinuria is confirmed alongside diffuse mesangiocapillary glomerulonephritis
  • Coders should ensure that the diagnosis is supported by appropriate clinical documentation, including laboratory results and any relevant imaging studies

Exclusion Criteria

Do NOT use N06.5 When
No specific exclusions found.

Related ICD-10 Codes

Related CPT Codes

81002CPT Code

Urinalysis, automated, with microscopy

Clinical Scenario

Used to confirm the presence of proteinuria in patients suspected of glomerular disorders.

Documentation Requirements

Results of urinalysis must be documented in the medical record.

Specialty Considerations

Nephrologists should ensure that urinalysis results are clearly linked to the diagnosis.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of conditions like isolated proteinuria with diffuse mesangiocapillary glomerulonephritis, improving the accuracy of patient records and facilitating better tracking of disease prevalence and outcomes.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of conditions like isolated proteinuria with diffuse mesangiocapillary glomerulonephritis, improving the accuracy of patient records and facilitating better tracking of disease prevalence and outcomes.

Reimbursement & Billing Impact

The transition to ICD-10 has allowed for more specific coding of conditions like isolated proteinuria with diffuse mesangiocapillary glomerulonephritis, improving the accuracy of patient records and facilitating better tracking of disease prevalence and outcomes.

Resources

Clinical References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Coding & Billing References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Frequently Asked Questions

What is the significance of genetic testing in N06.5?

Genetic testing can help identify hereditary factors contributing to isolated proteinuria and guide management and family counseling.