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ICD-10 Guide
ICD-10 CodesChapter 14: Diseases of the genitourinary systemN12

N12

Billable

Tubulo-interstitial nephritis, not specified as acute or chronic

Chapter 14:Diseases of the genitourinary system

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/18/2025

Code Description

ICD-10 N12 is a billable code used to indicate a diagnosis of tubulo-interstitial nephritis, not specified as acute or chronic.

Key Diagnostic Point:

Tubulo-interstitial nephritis (TIN) is a kidney disorder characterized by inflammation of the tubules and interstitial tissue of the kidney. This condition can arise from various etiologies, including infections, autoimmune diseases, and exposure to drugs or toxins. Pyelonephritis, a type of kidney infection, can lead to TIN if not treated promptly. Interstitial nephritis may also occur due to drug-induced nephropathy, where certain medications, such as non-steroidal anti-inflammatory drugs (NSAIDs) or antibiotics, cause damage to the renal interstitium. Urinary tract infections (UTIs) are common precursors to pyelonephritis and can exacerbate interstitial nephritis. Management often involves the use of antibiotics to treat underlying infections and the careful monitoring of renal function. The distinction between acute and chronic forms of TIN is crucial for treatment and prognosis, but this code does not specify the duration of the condition, making it essential for coders to rely on clinical documentation for accurate coding.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Lack of specification regarding acute or chronic status
  • Variety of potential underlying causes
  • Need for comprehensive clinical documentation
  • Differentiation from other renal conditions

Audit Risk Factors

  • Inadequate documentation of the cause of nephritis
  • Failure to specify acute or chronic status
  • Misidentification of related conditions
  • Inconsistent coding practices across providers

Specialty Focus

Medical Specialties

Nephrology

Documentation Requirements

Detailed history of renal function, laboratory results, and treatment plans.

Common Clinical Scenarios

Patients presenting with renal impairment, unexplained electrolyte imbalances, or recurrent UTIs.

Billing Considerations

Ensure that all relevant lab results and imaging studies are documented to support the diagnosis.

Urology

Documentation Requirements

Comprehensive assessment of urinary symptoms, imaging studies, and any surgical interventions.

Common Clinical Scenarios

Patients with obstructive uropathy or recurrent urinary tract infections leading to renal complications.

Billing Considerations

Document any surgical history or interventions that may contribute to renal function.

Coding Guidelines

Inclusion Criteria

Use N12 When
  • According to ICD
  • 10 guidelines, N12 should be used when the specific type of tubulo
  • interstitial nephritis is not documented
  • Coders should ensure that the documentation supports the diagnosis and consider the patient's clinical history

Exclusion Criteria

Do NOT use N12 When
No specific exclusions found.

Related CPT Codes

81002CPT Code

Urinalysis, automated, with microscopy

Clinical Scenario

Used to evaluate renal function in patients with suspected TIN.

Documentation Requirements

Document the reason for urinalysis and any relevant findings.

Specialty Considerations

Nephrologists may require additional tests to assess renal function.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of renal conditions, improving the accuracy of diagnoses and treatment plans. N12 provides a broad category for tubulo-interstitial nephritis, requiring careful documentation.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of renal conditions, improving the accuracy of diagnoses and treatment plans. N12 provides a broad category for tubulo-interstitial nephritis, requiring careful documentation.

Reimbursement & Billing Impact

The transition to ICD-10 has allowed for more specific coding of renal conditions, improving the accuracy of diagnoses and treatment plans. N12 provides a broad category for tubulo-interstitial nephritis, requiring careful documentation.

Resources

Clinical References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Coding & Billing References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Frequently Asked Questions

What is the difference between acute and chronic tubulo-interstitial nephritis?

Acute tubulo-interstitial nephritis typically presents suddenly and may resolve with treatment, while chronic tubulo-interstitial nephritis develops gradually and may lead to permanent kidney damage.