Analgesic nephropathy
ICD-10 N14.0 is a billable code used to indicate a diagnosis of analgesic nephropathy.
Analgesic nephropathy is a form of kidney damage that occurs due to the chronic use of analgesic medications, particularly nonsteroidal anti-inflammatory drugs (NSAIDs) and acetaminophen. This condition is characterized by interstitial nephritis, which is inflammation of the kidney's interstitial tissue, and can lead to renal impairment. Patients may present with symptoms such as flank pain, hematuria, and signs of urinary tract infections (UTIs). The condition can also be associated with pyelonephritis, which is an infection of the kidney, and hydronephrosis, a swelling of the kidney due to urine buildup. The pathophysiology involves direct nephrotoxic effects of analgesics, leading to tubular damage and interstitial fibrosis. Diagnosis typically involves a combination of clinical history, laboratory tests, and imaging studies. Management may include discontinuation of the offending analgesics, treatment of any underlying infections, and supportive care for renal function. In severe cases, patients may require dialysis or other interventions to manage renal failure.
Detailed history of analgesic use, renal function tests, and imaging studies.
Patients presenting with renal impairment and a history of chronic analgesic use.
Ensure clear documentation of the relationship between analgesic use and renal symptoms.
Comprehensive medication history and assessment of renal function.
Patients with chronic pain management on analgesics presenting with renal symptoms.
Document any referrals to nephrology for further evaluation.
Used to assess renal function in patients suspected of analgesic nephropathy.
Document the reason for testing and any relevant clinical findings.
Nephrology may require additional tests based on initial findings.
The primary cause of analgesic nephropathy is the chronic use of analgesic medications, particularly NSAIDs and acetaminophen, which can lead to kidney damage over time.