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v1.0.0
ICD-10 Guide
ICD-10 CodesN14.4

N14.4

Billable

Toxic nephropathy, not elsewhere classified

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/18/2025

Code Description

ICD-10 N14.4 is a billable code used to indicate a diagnosis of toxic nephropathy, not elsewhere classified.

Key Diagnostic Point:

Toxic nephropathy refers to kidney damage resulting from exposure to toxic substances, which can include drugs, heavy metals, and other environmental toxins. This condition can manifest as acute or chronic kidney injury, leading to a range of clinical symptoms such as decreased urine output, fluid retention, and electrolyte imbalances. Pyelonephritis, interstitial nephritis, and drug-induced nephropathy are common forms of toxic nephropathy. Pyelonephritis is an infection of the kidney that can occur secondary to urinary tract infections (UTIs), while interstitial nephritis is characterized by inflammation of the kidney interstitium, often due to medications or infections. Hydronephrosis, the swelling of a kidney due to a build-up of urine, can also be a complication of toxic nephropathy. Management typically involves identifying and removing the offending agent, supportive care, and in some cases, antibiotic therapy to treat underlying infections. Accurate diagnosis and coding are crucial for appropriate treatment and reimbursement.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Variety of potential toxic agents leading to nephropathy
  • Overlap with other nephropathies and infections
  • Need for detailed patient history to identify causative agents
  • Potential for acute vs. chronic classification

Audit Risk Factors

  • Inadequate documentation of toxic exposure
  • Failure to specify the type of nephropathy
  • Misclassification of acute vs. chronic conditions
  • Lack of supporting lab results or imaging

Specialty Focus

Medical Specialties

Nephrology

Documentation Requirements

Detailed patient history, lab results, and imaging studies to confirm diagnosis.

Common Clinical Scenarios

Patients presenting with acute kidney injury following medication use or exposure to toxins.

Billing Considerations

Ensure clear documentation of the toxic agent and its effects on kidney function.

Infectious Disease

Documentation Requirements

Documentation of urinary tract infections and their management, including antibiotic therapy.

Common Clinical Scenarios

Patients with recurrent UTIs leading to pyelonephritis and subsequent nephropathy.

Billing Considerations

Document the relationship between infections and nephropathy clearly.

Coding Guidelines

Inclusion Criteria

Use N14.4 When
  • Follow the official ICD
  • CM coding guidelines, ensuring that the diagnosis is supported by clinical documentation
  • Include any relevant laboratory or imaging findings that confirm the diagnosis of toxic nephropathy

Exclusion Criteria

Do NOT use N14.4 When
No specific exclusions found.

Related ICD-10 Codes

Related CPT Codes

80048CPT Code

Comprehensive metabolic panel

Clinical Scenario

Used to assess kidney function and electrolyte levels in patients with suspected nephropathy.

Documentation Requirements

Document the rationale for testing and results.

Specialty Considerations

Nephrology specialists should ensure all relevant lab results are included.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of nephropathies, including toxic nephropathy. This specificity aids in better tracking of nephrotoxic exposures and their outcomes, improving patient care and research.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of nephropathies, including toxic nephropathy. This specificity aids in better tracking of nephrotoxic exposures and their outcomes, improving patient care and research.

Reimbursement & Billing Impact

The transition to ICD-10 has allowed for more specific coding of nephropathies, including toxic nephropathy. This specificity aids in better tracking of nephrotoxic exposures and their outcomes, improving patient care and research.

Resources

Clinical References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Coding & Billing References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Frequently Asked Questions

What are the common causes of toxic nephropathy?

Common causes include exposure to nephrotoxic medications (like NSAIDs, antibiotics), heavy metals (like lead or mercury), and certain environmental toxins.