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v1.0.0
ICD-10 Guide
ICD-10 CodesChapter 14: Diseases of the genitourinary systemN16

N16

Billable

Renal tubulo-interstitial disorders in diseases classified elsewhere

Chapter 14:Diseases of the genitourinary system

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/18/2025

Code Description

ICD-10 N16 is a billable code used to indicate a diagnosis of renal tubulo-interstitial disorders in diseases classified elsewhere.

Key Diagnostic Point:

Renal tubulo-interstitial disorders encompass a range of conditions affecting the renal tubules and interstitial tissue, often secondary to other diseases. Pyelonephritis, an infection of the kidney, can lead to inflammation and damage to the renal interstitium. Interstitial nephritis, which may be acute or chronic, is characterized by inflammation of the renal interstitium and can be caused by infections, autoimmune diseases, or medications. Hydronephrosis, the swelling of a kidney due to a build-up of urine, can occur from obstruction or reflux and may lead to interstitial damage if not addressed. Drug-induced nephropathy is a significant concern, particularly with certain antibiotics and non-steroidal anti-inflammatory drugs (NSAIDs), which can cause acute interstitial nephritis. Urinary tract infections (UTIs) can also contribute to renal tubulo-interstitial disorders if they ascend to the kidneys. Management often involves antibiotics tailored to the specific infection or condition, with careful monitoring for potential nephrotoxic effects. Accurate coding requires a thorough understanding of the underlying conditions and their impact on renal function.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Variety of underlying diseases leading to renal tubulo-interstitial disorders.
  • Differentiation between acute and chronic conditions.
  • Potential for multiple concurrent diagnoses.
  • Need for precise documentation of causative factors.

Audit Risk Factors

  • Inadequate documentation of the underlying disease.
  • Failure to specify the type of renal disorder (acute vs. chronic).
  • Misclassification of drug-induced nephropathy.
  • Lack of clarity on the relationship between UTIs and renal disorders.

Specialty Focus

Medical Specialties

Nephrology

Documentation Requirements

Detailed history of renal function, laboratory results, and treatment plans.

Common Clinical Scenarios

Patients with chronic kidney disease secondary to interstitial nephritis or pyelonephritis.

Billing Considerations

Ensure clear documentation of the cause of renal impairment and any interventions performed.

Infectious Disease

Documentation Requirements

Comprehensive records of infections, antibiotic treatments, and response to therapy.

Common Clinical Scenarios

Patients with recurrent UTIs leading to renal complications.

Billing Considerations

Document the specific pathogens involved and the rationale for antibiotic choice.

Coding Guidelines

Inclusion Criteria

Use N16 When
  • According to ICD
  • 10 guidelines, N16 should be used when renal tubulo
  • interstitial disorders are secondary to other classified diseases
  • Coders must ensure that the primary condition is well
  • documented and that the renal disorder is appropriately linked to it

Exclusion Criteria

Do NOT use N16 When
  • Exclusions apply for primary renal disorders not classified under this code

Related CPT Codes

81002CPT Code

Urinalysis, automated, with microscopy

Clinical Scenario

Used to evaluate renal function and detect infections.

Documentation Requirements

Document the reason for urinalysis and findings.

Specialty Considerations

Nephrologists may require additional tests to assess renal function.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of renal tubulo-interstitial disorders, improving the accuracy of data collection and reimbursement processes. N16 provides a mechanism to capture complex cases that were previously underrepresented in ICD-9.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of renal tubulo-interstitial disorders, improving the accuracy of data collection and reimbursement processes. N16 provides a mechanism to capture complex cases that were previously underrepresented in ICD-9.

Reimbursement & Billing Impact

reimbursement processes. N16 provides a mechanism to capture complex cases that were previously underrepresented in ICD-9.

Resources

Clinical References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Coding & Billing References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Frequently Asked Questions

When should I use N16 instead of a more specific code?

Use N16 when the renal tubulo-interstitial disorder is secondary to another classified disease and no more specific code applies. Ensure that the underlying condition is well-documented.