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ICD-10 Guide
ICD-10 CodesO26.642

O26.642

Billable

Intrahepatic cholestasis of pregnancy, second trimester

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/08/2025

Code Description

ICD-10 O26.642 is a billable code used to indicate a diagnosis of intrahepatic cholestasis of pregnancy, second trimester.

Key Diagnostic Point:

Intrahepatic cholestasis of pregnancy (ICP) is a liver disorder that occurs during pregnancy, characterized by intense itching and elevated bile acids in the bloodstream. It typically arises in the second or third trimester and is associated with increased risks for both the mother and fetus, including preterm birth and fetal distress. The condition is believed to be related to hormonal changes and genetic predisposition, leading to impaired bile flow. Maternal symptoms often include pruritus, particularly on the palms and soles, and may be accompanied by jaundice in more severe cases. Diagnosis is confirmed through blood tests showing elevated liver enzymes and bile acids. Management focuses on symptom relief and monitoring fetal well-being, with potential interventions including medication to reduce bile acid levels and early delivery if necessary. Close collaboration with obstetricians and maternal-fetal medicine specialists is essential for optimal outcomes.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Requires understanding of liver function tests and their implications in pregnancy.
  • Differentiation from other pruritic conditions in pregnancy.
  • Potential for co-morbid conditions affecting liver function.
  • Need for interdisciplinary communication between obstetricians and hepatologists.

Audit Risk Factors

  • Inadequate documentation of symptoms and laboratory results.
  • Failure to document the management plan and follow-up.
  • Misclassification of the severity of the condition.
  • Lack of interdisciplinary notes from specialists.

Specialty Focus

Medical Specialties

Obstetrics and Gynecology

Documentation Requirements

Detailed documentation of maternal symptoms, laboratory results, and treatment plans is essential for accurate coding.

Common Clinical Scenarios

Patients presenting with itching and elevated bile acids, requiring monitoring and potential early delivery.

Billing Considerations

Consideration of the timing of symptoms and their impact on delivery planning.

Maternal-Fetal Medicine

Documentation Requirements

Comprehensive documentation of high-risk factors, fetal monitoring results, and interdisciplinary consultations.

Common Clinical Scenarios

Management of patients with ICP who are at risk for fetal distress or preterm labor.

Billing Considerations

Focus on the implications of ICP on fetal health and the need for potential interventions.

Coding Guidelines

Inclusion Criteria

Use O26.642 When
  • Follow official ICD
  • CM guidelines for coding obstetric conditions, ensuring accurate documentation of the trimester and any associated complications
  • Specific criteria for intrahepatic cholestasis must be met, including symptomatology and laboratory findings

Exclusion Criteria

Do NOT use O26.642 When
No specific exclusions found.

Related ICD-10 Codes

Related CPT Codes

99213CPT Code

Established patient office visit, Level 3

Clinical Scenario

Used for routine follow-up visits for patients with ICP.

Documentation Requirements

Documentation of symptoms, lab results, and management plan.

Specialty Considerations

Obstetricians should ensure thorough documentation of all relevant findings.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of conditions like ICP, improving the accuracy of data collection and reimbursement processes. It emphasizes the importance of documenting the trimester and associated complications.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of conditions like ICP, improving the accuracy of data collection and reimbursement processes. It emphasizes the importance of documenting the trimester and associated complications.

Reimbursement & Billing Impact

reimbursement processes. It emphasizes the importance of documenting the trimester and associated complications.

Resources

Clinical References

  • •
    ACOG Practice Bulletin on Intrahepatic Cholestasis of Pregnancy

Coding & Billing References

  • •
    ACOG Practice Bulletin on Intrahepatic Cholestasis of Pregnancy

Frequently Asked Questions

What are the common symptoms of intrahepatic cholestasis of pregnancy?

Common symptoms include intense itching, particularly on the palms and soles, and in some cases, jaundice. These symptoms typically arise in the second or third trimester and can significantly impact the quality of life for the mother.