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v1.0.0
ICD-10 Guide
ICD-10 CodesP04.6

P04.6

Billable

Newborn affected by maternal exposure to environmental chemical substances

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/11/2025

Code Description

ICD-10 P04.6 is a billable code used to indicate a diagnosis of newborn affected by maternal exposure to environmental chemical substances.

Key Diagnostic Point:

P04.6 refers to newborns who are affected by maternal exposure to environmental chemical substances, particularly noxious substances transmitted via the placenta or breast milk. This includes exposure to drugs, alcohol, and tobacco during pregnancy or lactation. Maternal drug use can lead to a range of neonatal complications, including withdrawal symptoms, growth restrictions, and developmental delays. Alcohol exposure can result in fetal alcohol spectrum disorders, characterized by physical, behavioral, and cognitive impairments. Tobacco exposure is associated with low birth weight, preterm birth, and respiratory issues in newborns. Accurate coding requires thorough documentation of maternal history, substance use patterns, and any resultant neonatal complications. The clinical management of these newborns often involves a multidisciplinary approach, including neonatologists, pediatricians, and social services, to address both immediate health concerns and long-term developmental needs.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Variability in maternal substance use patterns
  • Need for comprehensive maternal history documentation
  • Potential for multiple co-occurring conditions
  • Differentiation between types of substances and their effects

Audit Risk Factors

  • Inadequate documentation of maternal substance use
  • Failure to capture all relevant neonatal complications
  • Misclassification of substance exposure types
  • Inconsistent coding practices across providers

Specialty Focus

Medical Specialties

Neonatology

Documentation Requirements

Detailed maternal history, including substance use, prenatal care records, and neonatal assessment findings.

Common Clinical Scenarios

Newborns presenting with withdrawal symptoms, low birth weight, or developmental delays due to maternal substance exposure.

Billing Considerations

Consideration of the timing and amount of exposure, as well as the need for interdisciplinary care.

Pediatrics

Documentation Requirements

Comprehensive developmental assessments and follow-up care plans for affected newborns.

Common Clinical Scenarios

Pediatric evaluations for developmental delays or behavioral issues stemming from prenatal exposure.

Billing Considerations

Long-term monitoring for potential developmental and behavioral issues.

Coding Guidelines

Inclusion Criteria

Use P04.6 When
  • Follow the official ICD
  • CM guidelines for coding perinatal conditions, ensuring accurate documentation of maternal history and neonatal assessments
  • Specific criteria for P04
  • 6 include clear evidence of maternal exposure and its impact on the newborn's health

Exclusion Criteria

Do NOT use P04.6 When
No specific exclusions found.

Related ICD-10 Codes

Related CPT Codes

99460CPT Code

Initial hospital care, per day, for evaluation and management of a normal newborn

Clinical Scenario

Used when a newborn affected by maternal substance exposure requires initial evaluation.

Documentation Requirements

Document maternal history, neonatal assessment findings, and any interventions performed.

Specialty Considerations

Neonatologists should focus on withdrawal management and developmental assessments.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of perinatal conditions, improving the ability to capture the nuances of maternal substance exposure and its effects on newborns.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of perinatal conditions, improving the ability to capture the nuances of maternal substance exposure and its effects on newborns.

Reimbursement & Billing Impact

The transition to ICD-10 has allowed for more specific coding of perinatal conditions, improving the ability to capture the nuances of maternal substance exposure and its effects on newborns.

Resources

Clinical References

  • •
    CDC Guidelines on Maternal Substance Use

Coding & Billing References

  • •
    CDC Guidelines on Maternal Substance Use

Frequently Asked Questions

What documentation is needed to support coding P04.6?

Documentation should include a detailed maternal history of substance use, prenatal care records, and a thorough neonatal assessment that outlines any complications or symptoms related to the exposure.