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v1.0.0
ICD-10 Guide
ICD-10 CodesP22.0

P22.0

Billable

Respiratory distress syndrome of newborn

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/11/2025

Code Description

ICD-10 P22.0 is a billable code used to indicate a diagnosis of respiratory distress syndrome of newborn.

Key Diagnostic Point:

Respiratory distress syndrome (RDS) of the newborn, commonly referred to as hyaline membrane disease, is a significant condition affecting premature infants due to insufficient surfactant production in the lungs. This syndrome is characterized by the presence of respiratory distress shortly after birth, manifesting as tachypnea, grunting, nasal flaring, and retractions. The pathophysiology involves the collapse of alveoli due to the lack of surfactant, leading to impaired gas exchange and hypoxemia. RDS is most prevalent in infants born before 28 weeks of gestation and is less common in those born after 34 weeks. Transient tachypnea of the newborn (TTN) is a related condition that can occur in term infants, often due to retained fetal lung fluid, and typically resolves within 72 hours. Accurate diagnosis and management are critical, as RDS can lead to severe complications if not treated promptly. Treatment often includes supplemental oxygen, continuous positive airway pressure (CPAP), and exogenous surfactant therapy, which significantly improves outcomes for affected infants.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Differentiating between RDS and TTN based on clinical presentation and timing of onset.
  • Understanding the gestational age impact on the incidence and severity of RDS.
  • Navigating the documentation requirements for surfactant therapy and respiratory support.
  • Identifying co-morbid conditions that may complicate the diagnosis and treatment of RDS.

Audit Risk Factors

  • Inadequate documentation of gestational age and its impact on RDS.
  • Failure to document the specific type of respiratory support provided.
  • Misclassification of RDS severity leading to incorrect coding.
  • Lack of clarity in distinguishing RDS from TTN in clinical notes.

Specialty Focus

Medical Specialties

Neonatology

Documentation Requirements

Detailed records of respiratory assessments, interventions, and response to treatment.

Common Clinical Scenarios

Management of preterm infants with RDS requiring NICU admission and surfactant therapy.

Billing Considerations

Consideration of gestational age and associated comorbidities in coding.

Pediatrics

Documentation Requirements

Thorough history and physical examination notes, including respiratory status and treatment plans.

Common Clinical Scenarios

Follow-up care for infants discharged after treatment for RDS.

Billing Considerations

Awareness of long-term outcomes and potential complications related to RDS.

Coding Guidelines

Inclusion Criteria

Use P22.0 When
  • Follow the official ICD
  • CM guidelines for coding respiratory distress syndrome, ensuring accurate documentation of clinical findings, treatment modalities, and any associated conditions

Exclusion Criteria

Do NOT use P22.0 When
No specific exclusions found.

Related ICD-10 Codes

Related CPT Codes

94640CPT Code

Continuous positive airway pressure (CPAP) ventilation

Clinical Scenario

Used for infants with RDS requiring respiratory support.

Documentation Requirements

Document the indication for CPAP and the infant's response to treatment.

Specialty Considerations

Neonatologists should ensure accurate coding of respiratory support modalities.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of respiratory conditions, improving the ability to capture the nuances of neonatal respiratory distress syndromes, which aids in better tracking and management of these conditions.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of respiratory conditions, improving the ability to capture the nuances of neonatal respiratory distress syndromes, which aids in better tracking and management of these conditions.

Reimbursement & Billing Impact

The transition to ICD-10 has allowed for more specific coding of respiratory conditions, improving the ability to capture the nuances of neonatal respiratory distress syndromes, which aids in better tracking and management of these conditions.

Resources

Clinical References

  • •
    American Academy of Pediatrics - Neonatal Resuscitation Program

Coding & Billing References

  • •
    American Academy of Pediatrics - Neonatal Resuscitation Program

Frequently Asked Questions

What is the primary cause of respiratory distress syndrome in newborns?

The primary cause of respiratory distress syndrome in newborns is the deficiency of surfactant, which is critical for reducing surface tension in the alveoli and preventing their collapse. This condition is most commonly seen in preterm infants due to their immature lungs.