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ICD-10 Guide
ICD-10 CodesR31.21

R31.21

Asymptomatic microscopic hematuria

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/11/2025

Code Description

ICD-10 R31.21 is a billable code used to indicate a diagnosis of asymptomatic microscopic hematuria.

Key Diagnostic Point:

Asymptomatic microscopic hematuria is defined as the presence of red blood cells in the urine that is not visible to the naked eye and is detected through microscopic examination. This condition is often discovered incidentally during routine urinalysis or evaluation for other medical conditions. Microscopic hematuria can be a benign finding or indicative of underlying pathology, including urinary tract infections, kidney stones, glomerular diseases, or malignancies. The absence of symptoms such as pain, dysuria, or urgency distinguishes it from symptomatic hematuria. The clinical significance of asymptomatic microscopic hematuria necessitates further evaluation to rule out serious conditions, particularly in patients over 40 years of age or those with risk factors for urinary tract malignancies. Diagnostic approaches typically include repeat urinalysis, imaging studies such as ultrasound or CT scans, and possibly cystoscopy, depending on the clinical context and findings.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Need for thorough documentation of the absence of symptoms
  • Differentiation from symptomatic hematuria codes
  • Potential for underlying serious conditions requiring further investigation
  • Variability in clinical presentation and patient history

Audit Risk Factors

  • Inadequate documentation of the absence of symptoms
  • Failure to document follow-up evaluations or findings
  • Misclassification as symptomatic hematuria
  • Inconsistent lab results not corroborated by clinical findings

Specialty Focus

Medical Specialties

Internal Medicine

Documentation Requirements

Detailed patient history, including risk factors and absence of urinary symptoms.

Common Clinical Scenarios

Routine screening in patients with risk factors for renal disease or urinary tract malignancies.

Billing Considerations

Consideration of patient age and history of urinary tract issues when determining the need for further evaluation.

Emergency Medicine

Documentation Requirements

Acute care notes must include a thorough assessment of urinary symptoms and any immediate interventions.

Common Clinical Scenarios

Patients presenting with incidental findings on urinalysis during evaluation for unrelated complaints.

Billing Considerations

Rapid assessment of potential underlying causes, especially in older patients or those with risk factors.

Coding Guidelines

Inclusion Criteria

Use R31.21 When
  • Follow the official ICD
  • CM coding guidelines, ensuring that the diagnosis is supported by clinical documentation and laboratory findings
  • The absence of symptoms must be clearly stated in the medical record

Exclusion Criteria

Do NOT use R31.21 When
No specific exclusions found.

Related CPT Codes

81002CPT Code

Urinalysis, automated, with microscopy

Clinical Scenario

Used to confirm the presence of microscopic hematuria during routine evaluations.

Documentation Requirements

Ensure lab results are documented in the medical record.

Specialty Considerations

Internal medicine and urology may require additional imaging or follow-up based on findings.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of conditions like asymptomatic microscopic hematuria, improving the granularity of data for epidemiological studies and healthcare analytics.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of conditions like asymptomatic microscopic hematuria, improving the granularity of data for epidemiological studies and healthcare analytics.

Reimbursement & Billing Impact

The transition to ICD-10 has allowed for more specific coding of conditions like asymptomatic microscopic hematuria, improving the granularity of data for epidemiological studies and healthcare analytics.

Resources

Clinical References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Coding & Billing References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Frequently Asked Questions

What is the significance of asymptomatic microscopic hematuria?

Asymptomatic microscopic hematuria can indicate underlying conditions that may require further investigation, including urinary tract infections, kidney stones, or malignancies. It is essential to evaluate the patient thoroughly to rule out serious causes.