Drug induced fever
ICD-10 R50.2 is a billable code used to indicate a diagnosis of drug induced fever.
Drug induced fever (R50.2) refers to an elevation in body temperature resulting from the administration of medications. This condition can manifest as a mild to moderate fever, typically defined as a body temperature exceeding 100.4°F (38°C). The fever may arise from various pharmacological agents, including antibiotics, anticonvulsants, and non-steroidal anti-inflammatory drugs (NSAIDs). The pathophysiology often involves drug-induced hypersensitivity reactions, direct effects on the hypothalamic thermoregulatory center, or the release of pyrogens. Clinically, patients may present with additional symptoms such as chills, sweating, and malaise. Laboratory findings may include leukocytosis or elevated inflammatory markers, although these are not specific to drug-induced fever. Accurate identification of the offending agent is crucial, as discontinuation of the drug typically leads to resolution of the fever. Careful documentation of the patient's medication history and the timeline of fever onset in relation to drug administration is essential for proper coding and management.
Complete medication list, onset and duration of fever, and any associated symptoms.
Patients presenting with fever after starting new medications, particularly antibiotics or anticonvulsants.
Consider potential drug interactions and the patient's overall clinical picture.
Immediate assessment of vital signs, medication history, and any acute symptoms.
Patients with acute fever in the emergency department, especially those with recent medication changes.
Rapid identification of drug-induced fever is critical to prevent unnecessary treatments.
When a patient presents with fever and a medication history review is performed.
Document the visit details, including history, examination, and medical decision-making.
Internal medicine may require more detailed medication reconciliation.
Document the specific medications taken, the timeline of fever onset, any associated symptoms, and the clinical decision-making process leading to the diagnosis.
