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v1.0.0
ICD-10 Guide
ICD-10 CodesR59.9

R59.9

Enlarged lymph nodes, unspecified

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/11/2025

Code Description

ICD-10 R59.9 is a billable code used to indicate a diagnosis of enlarged lymph nodes, unspecified.

Key Diagnostic Point:

Enlarged lymph nodes, or lymphadenopathy, is a clinical finding characterized by the enlargement of lymph nodes, which can occur in various regions of the body. This condition may be a response to infection, inflammation, malignancy, or other systemic diseases. The lymphatic system plays a crucial role in the immune response, and lymph nodes act as filters for harmful substances. Symptoms associated with enlarged lymph nodes can include localized swelling, tenderness, and sometimes systemic symptoms such as fever, night sweats, or weight loss, depending on the underlying cause. The enlargement can be acute or chronic and may involve single or multiple lymph node groups. The unspecified nature of this code indicates that the specific cause of lymphadenopathy has not been determined, necessitating further investigation to identify the underlying pathology. Common causes include viral infections (e.g., mononucleosis), bacterial infections (e.g., tuberculosis), autoimmune disorders (e.g., lupus), and malignancies (e.g., lymphoma). Accurate diagnosis often requires a thorough clinical evaluation, including patient history, physical examination, and potentially imaging studies or biopsy.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Variety of potential underlying causes requiring differential diagnosis
  • Need for comprehensive documentation to support the diagnosis
  • Potential overlap with other lymph node-related codes
  • Variability in clinical presentation and associated symptoms

Audit Risk Factors

  • Insufficient documentation of the clinical findings
  • Failure to specify the location of the enlarged lymph nodes
  • Inadequate differentiation from other lymph node codes
  • Lack of supporting diagnostic tests or imaging results

Specialty Focus

Medical Specialties

Internal Medicine

Documentation Requirements

Detailed patient history, physical examination findings, and any relevant lab or imaging results must be documented to support the diagnosis of enlarged lymph nodes.

Common Clinical Scenarios

Patients presenting with fever, fatigue, and localized swelling in the neck or axilla, often requiring further evaluation for infectious or malignant causes.

Billing Considerations

Consideration of the patient's history, including recent infections, travel history, and exposure to known pathogens, is crucial for accurate coding.

Emergency Medicine

Documentation Requirements

Acute care documentation should include the onset of symptoms, associated systemic signs, and any immediate interventions or tests performed.

Common Clinical Scenarios

Patients presenting with acute lymphadenopathy due to infections such as cellulitis or abscess formation, requiring prompt evaluation and management.

Billing Considerations

In emergency settings, rapid assessment and documentation of the patient's clinical status and any immediate treatments are essential for accurate coding.

Coding Guidelines

Inclusion Criteria

Use R59.9 When
  • According to ICD
  • 10 coding guidelines, R59
  • 9 should be used when the clinical documentation does not specify the cause or location of the enlarged lymph nodes
  • Coders should ensure that the diagnosis is supported by the medical record and that all relevant clinical information is captured

Exclusion Criteria

Do NOT use R59.9 When
No specific exclusions found.

Related CPT Codes

88305CPT Code

Pathology examination of lymph node biopsy

Clinical Scenario

When a lymph node biopsy is performed to determine the cause of lymphadenopathy.

Documentation Requirements

Documentation of the biopsy procedure and pathology results must be included.

Specialty Considerations

Pathology reports should clearly indicate the findings related to lymphadenopathy.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specificity in coding lymphadenopathy, but the use of unspecified codes like R59.9 remains common. Coders must ensure that they are using the most accurate codes available to reflect the clinical situation.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specificity in coding lymphadenopathy, but the use of unspecified codes like R59.9 remains common. Coders must ensure that they are using the most accurate codes available to reflect the clinical situation.

Reimbursement & Billing Impact

The transition to ICD-10 has allowed for more specificity in coding lymphadenopathy, but the use of unspecified codes like R59.9 remains common. Coders must ensure that they are using the most accurate codes available to reflect the clinical situation.

Resources

Clinical References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Coding & Billing References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Frequently Asked Questions

When should I use R59.9?

Use R59.9 when the clinical documentation indicates enlarged lymph nodes but does not specify the cause or location. Ensure that the documentation supports the diagnosis and that further evaluation is planned.