ICD-10 Logo
ICDxICD-10 Medical Coding
ICD-10 Logo
ICDxICD-10 Medical Coding
ICD 10 CodesDiagnoses
ICD 10 CodesDiagnoses
ICD-10 Logo
ICDxICD-10 Medical Coding

Comprehensive ICD-10-CM code reference with AI-powered search capabilities.

© 2025 ICD Code Compass. All rights reserved.

Browse

  • All Chapters
  • All Categories
  • Diagnoses

Tools

  • AI Code Search
ICD-10-CM codes are maintained by the CDC and CMS. This tool is for reference purposes only.
v1.0.0
ICD-10 Guide
ICD-10 CodesR65.20

R65.20

Severe sepsis without septic shock

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/11/2025

Code Description

ICD-10 R65.20 is a billable code used to indicate a diagnosis of severe sepsis without septic shock.

Key Diagnostic Point:

Severe sepsis is a life-threatening condition that arises when the body's response to an infection injures its own tissues and organs. It is characterized by the presence of sepsis, which is defined as a systemic inflammatory response syndrome (SIRS) due to infection, along with evidence of organ dysfunction. Symptoms may include fever, chills, rapid heart rate, rapid breathing, confusion, and decreased urine output. Laboratory findings often reveal elevated white blood cell counts, abnormal liver function tests, and metabolic acidosis. Severe sepsis can progress to septic shock, but in this case, the patient does not exhibit the profound circulatory, cellular, and metabolic abnormalities associated with shock. Common causes include pneumonia, urinary tract infections, and abdominal infections. Early recognition and treatment are critical to improving outcomes.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Differentiating between severe sepsis and septic shock
  • Identifying organ dysfunction criteria
  • Understanding the underlying infection source
  • Documenting clinical findings accurately

Audit Risk Factors

  • Inadequate documentation of organ dysfunction
  • Misclassification of septic shock vs. severe sepsis
  • Failure to document the source of infection
  • Inconsistent clinical findings in the medical record

Specialty Focus

Medical Specialties

Internal Medicine

Documentation Requirements

Thorough documentation of vital signs, laboratory results, and clinical assessments is essential. Specific organ dysfunction must be noted.

Common Clinical Scenarios

Patients presenting with pneumonia or urinary tract infections leading to severe sepsis.

Billing Considerations

Internal medicine practitioners should ensure that all clinical findings are well-documented to support the diagnosis of severe sepsis.

Emergency Medicine

Documentation Requirements

Acute care documentation must include initial assessments, vital signs, and any interventions performed.

Common Clinical Scenarios

Patients arriving in the emergency department with fever, tachycardia, and altered mental status.

Billing Considerations

Emergency physicians should document the timeline of symptoms and interventions to support the diagnosis of severe sepsis.

Coding Guidelines

Inclusion Criteria

Use R65.20 When
  • According to ICD
  • 10 guidelines, severe sepsis is coded based on the presence of organ dysfunction and the underlying infection
  • Coders must ensure that the documentation supports the diagnosis and that all criteria for severe sepsis are met

Exclusion Criteria

Do NOT use R65.20 When
No specific exclusions found.

Related CPT Codes

99285CPT Code

Emergency department visit, high severity

Clinical Scenario

Used for patients presenting with severe sepsis symptoms.

Documentation Requirements

Document the severity of the condition and all relevant clinical findings.

Specialty Considerations

Emergency medicine providers should ensure that the visit level reflects the complexity of the case.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of severe sepsis, improving the ability to capture the complexity of the condition and its management.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of severe sepsis, improving the ability to capture the complexity of the condition and its management.

Reimbursement & Billing Impact

The transition to ICD-10 has allowed for more specific coding of severe sepsis, improving the ability to capture the complexity of the condition and its management.

Resources

Clinical References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Coding & Billing References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Frequently Asked Questions

What is the difference between severe sepsis and septic shock?

Severe sepsis involves organ dysfunction due to infection without the profound hypotension seen in septic shock. Septic shock is characterized by persistent low blood pressure despite adequate fluid resuscitation.