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v1.0.0
ICD-10 Guide
ICD-10 CodesR82.3

R82.3

Hemoglobinuria

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/11/2025

Code Description

ICD-10 R82.3 is a billable code used to indicate a diagnosis of hemoglobinuria.

Key Diagnostic Point:

Hemoglobinuria is the presence of free hemoglobin in the urine, which occurs when hemoglobin is released from red blood cells into the bloodstream and subsequently filtered by the kidneys. This condition can be indicative of hemolysis, where red blood cells are destroyed faster than they can be produced. Hemoglobinuria can present with dark or reddish-brown urine, and may be accompanied by symptoms such as fatigue, pallor, jaundice, and signs of acute kidney injury. Laboratory findings typically include positive urine tests for hemoglobin without the presence of red blood cells on microscopy, which differentiates it from hematuria. Common causes include hemolytic anemias, transfusion reactions, severe infections, and certain toxins. The clinical context is critical, as hemoglobinuria can lead to significant complications, including acute tubular necrosis if not addressed promptly. Accurate diagnosis often requires a combination of clinical evaluation, laboratory tests, and sometimes imaging studies to identify underlying causes.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Differentiation from hematuria
  • Need for comprehensive clinical context
  • Potential for multiple underlying causes
  • Variability in presentation and severity

Audit Risk Factors

  • Inadequate documentation of clinical findings
  • Failure to specify underlying causes
  • Misclassification with hematuria
  • Lack of supporting lab results

Specialty Focus

Medical Specialties

Internal Medicine

Documentation Requirements

Detailed history of symptoms, lab results, and any underlying conditions contributing to hemolysis.

Common Clinical Scenarios

Patients presenting with fatigue, jaundice, and dark urine, requiring evaluation for hemolytic anemia.

Billing Considerations

Ensure that all relevant lab tests are documented, including complete blood count and reticulocyte count.

Emergency Medicine

Documentation Requirements

Acute care documentation must include vital signs, initial lab results, and any immediate interventions.

Common Clinical Scenarios

Patients with acute hemolytic reactions post-transfusion or severe infections presenting with hemoglobinuria.

Billing Considerations

Rapid assessment and documentation of the patient's condition are critical for accurate coding.

Coding Guidelines

Inclusion Criteria

Use R82.3 When
  • Follow official ICD
  • CM guidelines for coding symptoms and abnormal findings, ensuring that the underlying cause is documented when known

Exclusion Criteria

Do NOT use R82.3 When
No specific exclusions found.

Related CPT Codes

85025CPT Code

Complete Blood Count (CBC) with differential

Clinical Scenario

Used to evaluate for anemia and hemolysis in patients with hemoglobinuria.

Documentation Requirements

Document the reason for the CBC and any relevant findings.

Specialty Considerations

Internal medicine may require additional tests based on findings.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of conditions like hemoglobinuria, improving the ability to capture clinical nuances and support better patient care.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of conditions like hemoglobinuria, improving the ability to capture clinical nuances and support better patient care.

Reimbursement & Billing Impact

The transition to ICD-10 has allowed for more specific coding of conditions like hemoglobinuria, improving the ability to capture clinical nuances and support better patient care.

Resources

Clinical References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Coding & Billing References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Frequently Asked Questions

What is the difference between hemoglobinuria and hematuria?

Hemoglobinuria is the presence of free hemoglobin in urine, while hematuria refers to the presence of intact red blood cells. Differentiation is crucial for accurate diagnosis and treatment.