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v1.0.0
ICD-10 Guide
ICD-10 CodesR82.81

R82.81

Pyuria

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/11/2025

Code Description

ICD-10 R82.81 is a billable code used to indicate a diagnosis of pyuria.

Key Diagnostic Point:

Pyuria is defined as the presence of white blood cells (WBCs) in the urine, which is often indicative of an underlying infection or inflammation in the urinary tract. Clinically, pyuria is characterized by cloudy urine, which may also have a foul odor. It can be detected through urinalysis, where the presence of WBCs is quantified. Pyuria can occur in various conditions, including urinary tract infections (UTIs), kidney infections, and sexually transmitted infections. It may also be associated with non-infectious causes such as interstitial nephritis or certain malignancies. The clinical significance of pyuria lies in its potential to indicate a serious underlying condition, necessitating further investigation and management. In the absence of other symptoms, pyuria may not always correlate with a UTI, making it essential for clinicians to consider the patient's overall clinical picture and history when interpreting this finding.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Differentiating between infectious and non-infectious causes
  • Variability in laboratory reporting standards
  • Need for correlation with clinical symptoms
  • Potential overlap with other urinary symptoms

Audit Risk Factors

  • Inadequate documentation of the clinical rationale for testing
  • Failure to document associated symptoms or conditions
  • Misinterpretation of lab results leading to incorrect coding
  • Inconsistent use of terminology in clinical notes

Specialty Focus

Medical Specialties

Internal Medicine

Documentation Requirements

Clear documentation of symptoms, lab findings, and any associated conditions is essential. The clinician should note the patient's history and any relevant risk factors.

Common Clinical Scenarios

Patients presenting with urinary symptoms such as dysuria, frequency, or urgency, alongside pyuria findings.

Billing Considerations

Consideration of chronic conditions like diabetes or immunosuppression that may predispose patients to infections.

Emergency Medicine

Documentation Requirements

Acute care documentation must include a thorough history and physical examination, noting any acute symptoms and lab results.

Common Clinical Scenarios

Patients presenting with acute flank pain, fever, or other systemic symptoms alongside pyuria.

Billing Considerations

Rapid assessment of potential serious conditions such as pyelonephritis or urosepsis.

Coding Guidelines

Inclusion Criteria

Use R82.81 When
  • Coders should refer to the official ICD
  • CM guidelines, ensuring that the code is used in conjunction with appropriate clinical documentation that supports the diagnosis of pyuria

Exclusion Criteria

Do NOT use R82.81 When
No specific exclusions found.

Related CPT Codes

81002CPT Code

Urinalysis, automated, with microscopy

Clinical Scenario

Used when a urinalysis is performed to evaluate for pyuria.

Documentation Requirements

Documentation must include the reason for the urinalysis and any relevant clinical findings.

Specialty Considerations

In emergency settings, rapid results may influence immediate treatment decisions.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of conditions like pyuria, improving the accuracy of diagnoses and treatment tracking.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of conditions like pyuria, improving the accuracy of diagnoses and treatment tracking.

Reimbursement & Billing Impact

The transition to ICD-10 has allowed for more specific coding of conditions like pyuria, improving the accuracy of diagnoses and treatment tracking.

Resources

Clinical References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Coding & Billing References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Frequently Asked Questions

What is the significance of pyuria in clinical practice?

Pyuria is a significant clinical finding that often indicates an underlying infection or inflammation in the urinary tract, necessitating further evaluation and management.