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ICD-10 Guide
ICD-10 CodesR85.3

R85.3

Abnormal level of substances chiefly nonmedicinal as to source in specimens from digestive organs and abdominal cavity

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/11/2025

Code Description

ICD-10 R85.3 is a billable code used to indicate a diagnosis of abnormal level of substances chiefly nonmedicinal as to source in specimens from digestive organs and abdominal cavity.

Key Diagnostic Point:

R85.3 is used to classify abnormal laboratory findings related to nonmedicinal substances found in specimens obtained from the digestive organs and abdominal cavity. This may include abnormal levels of substances such as enzymes, proteins, or metabolites that are not derived from medications but may indicate underlying pathological processes. Commonly, these findings arise from conditions affecting the liver, pancreas, or gastrointestinal tract. For instance, elevated levels of bilirubin may suggest liver dysfunction, while abnormal pancreatic enzyme levels could indicate pancreatitis. The clinical significance of these findings often necessitates further investigation to determine the underlying cause, which may include imaging studies or additional laboratory tests. Accurate coding of R85.3 requires careful documentation of the specific substances tested and the clinical context in which the tests were performed.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Variety of nonmedicinal substances that can be tested
  • Need for precise documentation of laboratory findings
  • Differentiation from similar codes related to medicinal substances
  • Potential overlap with other abnormal findings codes

Audit Risk Factors

  • Inadequate documentation of laboratory results
  • Failure to specify the source of the abnormal findings
  • Misclassification of findings as medicinal rather than nonmedicinal
  • Lack of correlation between clinical findings and laboratory results

Specialty Focus

Medical Specialties

Internal Medicine

Documentation Requirements

Detailed lab results and clinical correlation must be documented, including the specific substances tested and their clinical significance.

Common Clinical Scenarios

Patients presenting with unexplained abdominal pain, jaundice, or changes in bowel habits may undergo testing that reveals abnormal levels of nonmedicinal substances.

Billing Considerations

Ensure that the clinical context is well-documented to support the use of R85.3, particularly in cases where multiple tests are performed.

Emergency Medicine

Documentation Requirements

Acute care documentation must include immediate lab results and any interventions taken based on those results.

Common Clinical Scenarios

Patients presenting with acute abdominal pain or altered mental status may have abnormal lab findings that require urgent attention.

Billing Considerations

Rapid documentation is crucial; ensure that abnormal findings are clearly linked to the presenting symptoms.

Coding Guidelines

Inclusion Criteria

Use R85.3 When
  • Follow the official ICD
  • CM coding guidelines, ensuring that the code is used only when the abnormal findings are specifically related to nonmedicinal substances from digestive organs or the abdominal cavity
  • Documentation must support the diagnosis and the clinical rationale for testing

Exclusion Criteria

Do NOT use R85.3 When
No specific exclusions found.

Related CPT Codes

80053CPT Code

Comprehensive metabolic panel

Clinical Scenario

Used to evaluate overall health and detect metabolic disorders, often leading to the use of R85.3 if abnormal findings are noted.

Documentation Requirements

Document the specific tests performed and the results that led to the diagnosis.

Specialty Considerations

Internal medicine and family practice frequently utilize this panel.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of abnormal findings, improving the granularity of data collected for research and clinical purposes. R85.3 provides a clear distinction for nonmedicinal findings, which aids in better patient management and treatment planning.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of abnormal findings, improving the granularity of data collected for research and clinical purposes. R85.3 provides a clear distinction for nonmedicinal findings, which aids in better patient management and treatment planning.

Reimbursement & Billing Impact

The transition to ICD-10 has allowed for more specific coding of abnormal findings, improving the granularity of data collected for research and clinical purposes. R85.3 provides a clear distinction for nonmedicinal findings, which aids in better patient management and treatment planning.

Resources

Clinical References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Coding & Billing References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Frequently Asked Questions

What types of substances are included under R85.3?

R85.3 includes abnormal levels of substances such as enzymes, proteins, or metabolites that are not derived from medications and are found in specimens from the digestive organs and abdominal cavity.