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ICD-10 Guide
ICD-10 CodesR87.3

R87.3

Abnormal level of substances chiefly nonmedicinal as to source in specimens from female genital organs

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/11/2025

Code Description

ICD-10 R87.3 is a billable code used to indicate a diagnosis of abnormal level of substances chiefly nonmedicinal as to source in specimens from female genital organs.

Key Diagnostic Point:

R87.3 is used to classify abnormal laboratory findings related to the presence of nonmedicinal substances in specimens obtained from female genital organs. This may include abnormal levels of substances such as hormones, proteins, or metabolites that are not derived from medications. The clinical significance of these findings can vary widely, ranging from benign conditions to serious pathologies. Common causes of abnormal levels may include hormonal imbalances, infections, or neoplastic processes. Symptoms may be nonspecific, including abnormal vaginal discharge, pelvic pain, or menstrual irregularities. The diagnostic approach typically involves a thorough clinical history, physical examination, and targeted laboratory tests to identify the underlying cause of the abnormal findings. Accurate coding requires careful documentation of the clinical context and the specific substances involved.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Variety of potential underlying conditions
  • Need for precise documentation of laboratory findings
  • Differentiation from similar codes
  • Potential for overlapping symptoms with other diagnoses

Audit Risk Factors

  • Inadequate documentation of laboratory results
  • Failure to specify the substance involved
  • Misinterpretation of abnormal findings
  • Inconsistent coding across providers

Specialty Focus

Medical Specialties

Internal Medicine

Documentation Requirements

Detailed clinical history, laboratory results, and any relevant imaging studies.

Common Clinical Scenarios

Evaluation of abnormal Pap smears, hormonal assays, or pelvic ultrasound findings.

Billing Considerations

Ensure that the clinical significance of abnormal findings is clearly documented.

Emergency Medicine

Documentation Requirements

Acute care notes, including vital signs, presenting symptoms, and immediate lab results.

Common Clinical Scenarios

Acute pelvic pain with abnormal lab findings indicating possible infection or hemorrhage.

Billing Considerations

Rapid assessment and documentation of findings are crucial for accurate coding.

Coding Guidelines

Inclusion Criteria

Use R87.3 When
  • Follow the official ICD
  • CM coding guidelines, ensuring that the code is used only when the abnormal findings are specifically related to nonmedicinal substances from female genital specimens
  • Document the clinical context and any relevant laboratory results

Exclusion Criteria

Do NOT use R87.3 When
No specific exclusions found.

Related CPT Codes

88141CPT Code

Cytopathology, cervical or vaginal (Pap smear)

Clinical Scenario

Used when a Pap smear indicates abnormal findings requiring further investigation.

Documentation Requirements

Document the results of the Pap smear and any follow-up tests.

Specialty Considerations

Gynecological specialists should ensure accurate coding based on lab results.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of abnormal findings, improving the granularity of data collection and analysis. R87.3 provides a clear distinction for nonmedicinal substances, enhancing clinical understanding and treatment planning.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of abnormal findings, improving the granularity of data collection and analysis. R87.3 provides a clear distinction for nonmedicinal substances, enhancing clinical understanding and treatment planning.

Reimbursement & Billing Impact

The transition to ICD-10 has allowed for more specific coding of abnormal findings, improving the granularity of data collection and analysis. R87.3 provides a clear distinction for nonmedicinal substances, enhancing clinical understanding and treatment planning.

Resources

Clinical References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Coding & Billing References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Frequently Asked Questions

What types of substances are classified under R87.3?

R87.3 includes abnormal levels of nonmedicinal substances such as hormones, proteins, or metabolites found in specimens from female genital organs, which may indicate various underlying conditions.