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v1.0.0
ICD-10 Guide
ICD-10 CodesB16

B16

Acute hepatitis B with delta-agent

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 B16 is a billable code used to indicate a diagnosis of acute hepatitis b with delta-agent.

Key Diagnostic Point:

Acute hepatitis B with delta-agent is a viral infection caused by the hepatitis B virus (HBV) in conjunction with the hepatitis D virus (HDV). This condition is characterized by the rapid onset of liver inflammation, which can lead to significant liver damage if not managed appropriately. The delta agent, or hepatitis D virus, requires the presence of HBV to replicate, making co-infection particularly severe. Transmission occurs primarily through exposure to infectious body fluids, including blood, semen, and vaginal secretions. High-risk populations include intravenous drug users, individuals with multiple sexual partners, and those with occupational exposure to blood. Symptoms may include jaundice, fatigue, abdominal pain, and elevated liver enzymes. Chronic management focuses on monitoring liver function, potential antiviral therapy, and lifestyle modifications to prevent further liver damage. Complications can include acute liver failure, chronic hepatitis, cirrhosis, and hepatocellular carcinoma. Early diagnosis and intervention are crucial to mitigate these risks and improve patient outcomes.

Code Complexity Analysis

Complexity Rating: High

High Complexity

Complexity Factors

  • Co-infection with hepatitis D complicates the clinical picture.
  • Differentiating between acute and chronic hepatitis can be challenging.
  • Requires understanding of transmission routes and risk factors.
  • Management may involve multiple specialties, increasing documentation complexity.

Audit Risk Factors

  • Inadequate documentation of co-infection status.
  • Failure to document risk factors for transmission.
  • Lack of follow-up care documentation.
  • Inconsistent coding of acute vs. chronic hepatitis.

Specialty Focus

Medical Specialties

Infectious Disease

Documentation Requirements

Detailed patient history, risk factors, laboratory results, and treatment plans.

Common Clinical Scenarios

Diagnosis of acute hepatitis in high-risk populations, management of co-infections.

Billing Considerations

Ensure all laboratory tests are documented to support the diagnosis of acute hepatitis B with delta-agent.

Gastroenterology

Documentation Requirements

Comprehensive liver function tests, imaging studies, and treatment response documentation.

Common Clinical Scenarios

Management of liver complications, monitoring for cirrhosis or hepatocellular carcinoma.

Billing Considerations

Document any liver biopsies or imaging studies performed to assess liver damage.

Coding Guidelines

Inclusion Criteria

Use B16 When
  • Follow the official ICD
  • CM coding guidelines for infectious diseases
  • Ensure accurate documentation of the acute nature of the hepatitis and the presence of the delta agent
  • infection

Exclusion Criteria

Do NOT use B16 When
  • Exclude other forms of hepatitis that do not involve HBV and HDV co

Related Codes

Child Codes

4 codes
B16.0
Acute hepatitis B with delta-agent
B16.1
Acute hepatitis B with delta-agent infection
B16.2
Acute hepatitis B with delta-agent infection
B16.9
Acute hepatitis B without delta-agent and without hepatic coma

Related CPT Codes

86803CPT Code

Hepatitis B surface antigen (HBsAg) test

Clinical Scenario

Used to confirm diagnosis of acute hepatitis B.

Documentation Requirements

Document the reason for testing and results.

Specialty Considerations

Infectious disease specialists should ensure comprehensive testing for co-infections.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of hepatitis conditions, including the differentiation of acute hepatitis B with delta-agent, which was less clearly defined in ICD-9. This specificity aids in better tracking of disease prevalence and management outcomes.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of hepatitis conditions, including the differentiation of acute hepatitis B with delta-agent, which was less clearly defined in ICD-9. This specificity aids in better tracking of disease prevalence and management outcomes.

Reimbursement & Billing Impact

The transition to ICD-10 has allowed for more specific coding of hepatitis conditions, including the differentiation of acute hepatitis B with delta-agent, which was less clearly defined in ICD-9. This specificity aids in better tracking of disease prevalence and management outcomes.

Resources

Clinical References

  • •
    CDC Hepatitis B Information

Coding & Billing References

  • •
    CDC Hepatitis B Information

Frequently Asked Questions

What is the significance of the delta agent in hepatitis B?

The delta agent, or hepatitis D virus, complicates hepatitis B infections and can lead to more severe liver disease. It requires the presence of hepatitis B to replicate, making co-infection particularly dangerous.