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v1.0.0
ICD-10 Guide
ICD-10 CodesA52

A52

Late syphilis

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 A52 is a billable code used to indicate a diagnosis of late syphilis.

Key Diagnostic Point:

Late syphilis is the final stage of syphilis, a sexually transmitted infection caused by the bacterium Treponema pallidum. This stage typically occurs years after the initial infection if left untreated. Clinically, late syphilis can manifest as gummatous syphilis, where soft, tumor-like growths (gummas) develop in various tissues, or as neurosyphilis, affecting the central nervous system. Patients may experience a range of symptoms, including but not limited to, skin lesions, neurological deficits, and cardiovascular complications. Diagnosis is primarily through serological testing, including non-treponemal tests (e.g., RPR, VDRL) and treponemal tests (e.g., FTA-ABS). Treatment involves the administration of benzathine penicillin G, which is effective in eradicating the infection and preventing further complications. Contact tracing is crucial in managing syphilis, as it helps identify and treat sexual partners to prevent reinfection and further transmission of the disease.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Differentiating between late syphilis and other stages of syphilis.
  • Understanding the various manifestations of late syphilis (e.g., gummatous, neurosyphilis).
  • Proper documentation of serological test results.
  • Ensuring accurate coding based on clinical findings and treatment provided.

Audit Risk Factors

  • Inadequate documentation of clinical findings.
  • Failure to document serological test results.
  • Lack of evidence for contact tracing efforts.
  • Misclassification of the stage of syphilis.

Specialty Focus

Medical Specialties

Infectious Disease

Documentation Requirements

Detailed clinical notes on symptoms, test results, and treatment plans.

Common Clinical Scenarios

Patients presenting with neurological symptoms or gummatous lesions.

Billing Considerations

Ensure comprehensive documentation of all serological tests and follow-up care.

Primary Care

Documentation Requirements

Thorough history of sexual health, risk factors, and partner notification efforts.

Common Clinical Scenarios

Routine screening in high-risk populations and management of syphilis cases.

Billing Considerations

Documenting patient education on STIs and safe sex practices.

Coding Guidelines

Inclusion Criteria

Use A52 When
  • According to the official ICD
  • 10 coding guidelines, A52 should be used when the patient has a confirmed diagnosis of late syphilis, supported by clinical findings and serological test results
  • It is important to document the specific manifestations and any complications associated with the condition

Exclusion Criteria

Do NOT use A52 When
No specific exclusions found.

Related Codes

Child Codes

33 codes
A52.0
Early syphilis, symptomatic
A52.00
Cardiovascular syphilis, unspecified
A52.01
Syphilitic aneurysm of aorta
A52.02
Syphilitic aortitis
A52.03
Syphilitic endocarditis
A52.04
Syphilitic cerebral arteritis
A52.05
Other cerebrovascular syphilis
A52.06
Other syphilitic heart involvement
A52.09
Other cardiovascular syphilis
A52.1
Early syphilis, symptomatic
A52.10
Symptomatic neurosyphilis, unspecified
A52.11
Tabes dorsalis
A52.12
Other cerebrospinal syphilis
A52.13
Late syphilitic meningitis
A52.14
Late syphilitic encephalitis
A52.15
Late syphilitic neuropathy
A52.16
Charcôt's arthropathy (tabetic)
A52.17
General paresis
A52.19
Other symptomatic neurosyphilis
A52.2
Late syphilis, latent
A52.3
Neurological syphilis
A52.7
Late syphilis, unspecified
A52.71
Late syphilitic oculopathy
A52.72
Syphilis of lung and bronchus
A52.73
Symptomatic late syphilis of other respiratory organs
A52.74
Syphilis of liver and other viscera
A52.75
Syphilis of kidney and ureter
A52.76
Other genitourinary symptomatic late syphilis
A52.77
Syphilis of bone and joint
A52.78
Syphilis of other musculoskeletal tissue
A52.79
Other symptomatic late syphilis
A52.8
Late syphilis, other and unspecified
A52.9
Late syphilis, unspecified

Related CPT Codes

86592CPT Code

Syphilis serology test

Clinical Scenario

Used to confirm diagnosis of late syphilis.

Documentation Requirements

Document the type of serological tests performed and results.

Specialty Considerations

Infectious disease specialists may require additional details on test interpretation.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of late syphilis, improving the accuracy of data collection and reporting. This specificity aids in better tracking of syphilis trends and outcomes, ultimately enhancing public health responses.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of late syphilis, improving the accuracy of data collection and reporting. This specificity aids in better tracking of syphilis trends and outcomes, ultimately enhancing public health responses.

Reimbursement & Billing Impact

The transition to ICD-10 has allowed for more specific coding of late syphilis, improving the accuracy of data collection and reporting. This specificity aids in better tracking of syphilis trends and outcomes, ultimately enhancing public health responses.

Resources

Clinical References

  • •
    CDC Syphilis Fact Sheet

Coding & Billing References

  • •
    CDC Syphilis Fact Sheet

Frequently Asked Questions

What are the common symptoms of late syphilis?

Common symptoms include gummas, neurological issues, and cardiovascular problems. Patients may also experience systemic symptoms like fever and malaise.

How is late syphilis treated?

Treatment typically involves benzathine penicillin G, administered intramuscularly. The dosage and duration depend on the severity of the disease.